Table 4

Cytotoxicity (LD50in mg/mL) of extract and selectivity index based on MIC of extract after 12 hours of extracts from thirteen plants examined
Plant species Cytotoxicity A. fumigatus C. albicans C. neoformans
Brachylaena discolor 0.004 0.01 0.01 0.05
Zanthoxylum capense 0.008 0.2 0.05 0.1
Clerodendrum glabrum 0.172 4.3 0.55 2.15
Heteromorpha trifoliata 0.043 0.27 0.55 0.27
Apodytes dimidiata 0.003 0.01 0.01 0.04
Strychnos mitis 0.043 0.14 0.14 0.07
Maesa lanceolata 0.104 0.34 0.65 0.65
Indigofera frutescens 0.052 0.65 0.33 0.33
Leucosidea sericea 0.016 0.1 0.05 0.2
Melia azedarach 0.145 0.47 0.91 0.23
Clausena anisata 0.053 2.65 0.08 0.33
Cyathea dregei 0.017 0.11 0.01 0.11
Milletia grandis 0.021 0.53 0.13 0.03

Therapeutic index calculated by dividing LD50 by MIC.

Adamu et al.

Adamu et al. BMC Complementary and Alternative Medicine 2012 12:213   doi:10.1186/1472-6882-12-213

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