Apoptosis effect of EGCG on NPC cells. The upper panel shows the apoptosis frequency of TW01 parental cell increased from 4.3% up to 63.6% after 40μM EGCG treatment, while only up to 12.7% is noted in the sphere-derived cells. The lower panel shows EGCG-induced TW01 parental cell apoptosis was significantly correlated with a dose-dependent trend but was not as effective in TW01 sphere-derived cells.
Lin et al. BMC Complementary and Alternative Medicine 2012 12:201 doi:10.1186/1472-6882-12-201