Cucurbitacin B inhibits growth of human breast cancer cells. MCF-7 and MDA-MB-231 were treated with cucurbitacin B at a final concentration, ranging from 0 to 100 μM for 48 hr. Growth inhibition was determined by the MTT assay. The percentage of cell survival was calculated by defining the absorption of cells without cucurbitacin B treatment as 100%. Results are the average of three independent experiments *, p<0.05 (treated vs untreated control).
Duangmano et al. BMC Complementary and Alternative Medicine 2012 12:185 doi:10.1186/1472-6882-12-185