Table 3

The genotype distribution of UCP-1 polymorphisms in the dampness-phlegm and non-dampness-phlegm groups compared with the normal group
Model SNPs Genotype Normal Non-dampness OR [95% CI] p Dampness OR [95% CI] p
phlegm Phlegm
Allele A-3826G A 619 (53.27) 1,032 (51.43) 1.097 0.2586 575 (49.57) 1.205 0.0443
G 543 (46.73) 978 (48.66) (0.934,1.290) 585 (50.43) (1.005,1.444)
A-1766G A 871 (75.22) 1512 (75.6) 0.968 0.7371 873 (75.91) 0.98 0.8548
G 287 (24.78) 488 (24.4) (0.802,1.169) 277 (24.09) (0.793, 1.212)
Ala64Thr A 77 (6.58) 130 (6.45) 0.984 0.9226 91 (7.84) 0.879 0.468
G 1,093 (93.42) 1,886 (93.55) (0.710,1.364) 1,069 (91.67) (0.621,1.245)
Do A-3826G AA 164 (28.23) 267 (26.57) 1.168 0.2319 129 (22.24) 1.508 0.0065
AG+GG 417 (71.77) 738 (73.43) (0.906,1.506) 451 (77.76) (1.122, 2.028)
A-1766G AA 335 (57.86) 563 (56.3) 1.066 0.5872 328 (57.04) 1.023 0.8644
AG+GG 244 (42.14) 437 (43.7) (0.846,1.344) 247 (42.96) (0.789, 1.327)
Ala64Thr GG 508 (86.84) 879 (87.2) 0.989 0.9489 492 (84.83) 1.087 0.6157
GA+AA 77 (13.16) 129 (12.8) (0.704,1.389) 88 (15.17) (0.762, 1.583)
R A-3826G AA+AG 455 (78.31) 765 (76.12) 1.093 0.5257 446 (76.90) 1.092 0.5749
GG 126 (21.69) 240 (23.38) (0.831,1.437) 134 (23.10) (0.803,1.485)
A-1766G AA+AG 536 (92.57) 949 (94.9) 0.606 0.0423 545 (94.78) 0.801 0.4183
GG 43 (7.43) 51 (5.1) (0.374, 0.983) 30 (5.22) (0.468,1.371)
Ala64Thr GG+GA 585 (100) 1,007 (99.9) ND ND 577 (99.48) ND ND
AA 0 (0) 1 (0.1) 3 (0.52)

* The values indicate the frequency of subjects (%). OR (95% CI) and Siga, Sigb value were calculated using a binary logistical regression model adjusted for sex, age, smoking, and drinking with normal versus non-dampness-phlegm, normal versus dampness-phlegm . Do and R denote dominant and recessive models, respectively. CI: confidence interval. P-values with statistical significance were presented in bold (<0.05).

Lim et al.

Lim et al. BMC Complementary and Alternative Medicine 2012 12:180   doi:10.1186/1472-6882-12-180

Open Data