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Open Access Research article

Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptors

Cheng-Li Wang1, Chiu-Ying Lu1, Chia-Chen Pi1, Yu-Jing Zhuang1, Ching-Liang Chu2, Wen-Hsiung Liu1 and Chun-Jen Chen1*

Author Affiliations

1 Department of Biochemical Science and Technology, National Taiwan University, Taipei, Taiwan, 10617, Republic of China

2 Graduate Institute of Immunology, National Taiwan University, College of Medicine, Taipei, Taiwan, 100, Republic of China

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BMC Complementary and Alternative Medicine 2012, 12:119  doi:10.1186/1472-6882-12-119

Published: 10 August 2012

Additional files

Additional file 1 :

Zymosan-stimulated macrophage activation was blocked by anti-Dectin-1 and anti-CR3 antibodies.

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Additional file 2 :

PS-F2-stimulated macrophage activation does not require TLR2.

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Additional file 3 :

LPS-stimulated macrophage activation was blocked by the inhibitors of MAPK and NF-κB activation.

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Open Data