Table 4

Adjusteda OR (95% CI) for the association between estrogenic botanical supplement use and hormone-related symptoms during last years of 30-month survey

Ginseng

Red Clover

Alfalfa

DHEA


No

Yes

Adjusteda OR (95% CI)

No

Yes

Adjusteda OR (95% CI)

No

Yes

Adjusteda OR (95% CI)

No

Yes

Adjusteda OR (95% CI)


Hot flashes

No

179

19

1.00

191

7

1.00

187

11

1.00

187

11

1.00

Yes

485

84

1.41 (0.76-2.63)

538

31

0.99 (0.34-2.85)

549

20

0.43 (0.17-1.08)

556

13

0.33 (0.14-0.82)

Vaginal discharge

No

427

53

1.00

457

23

1.00

460

20

1.00

466

14

1.00

Yes

237

50

1.81 (1.12-2.93)

272

15

0.92 (0.42-2.05)

276

11

0.94 (0.41-2.20)

277

10

1.15 (0.48-2.73)

Weight gain

No

234

37

1.00

253

18

1.00

257

14

1.00

262

9

1.00

Yes

430

66

0.94 (0.57-1.55)

476

20

0.41 (0.19-0.91)

479

17

0.76 (0.33-1.76)

481

15

0.88 (0.36-2.11)

Unhappy with bodily appearance

No

221

17

1.00

225

13

1.00

226

12

1.00

230

8

1.00

Yes

443

86

2.58 (1.38-4.81)

504

25

0.49 (0.21-1.17)

510

19

0.67 (0.28-1.60)

513

16

0.76 (0.30-1.93)

Forgetfulness

No

147

13

1.00

153

7

1.00

154

6

1.00

156

4

1.00

Yes

517

90

2.19 (1.11-4.33)

576

31

1.09 (0.40-2.98)

582

25

1.09 (0.39-3.02)

587

20

1.38 (0.43-4.42)

Tendency to take naps, stay in bed

No

326

39

1.00

346

19

1.00

352

13

1.00

357

8

1.00

Yes

338

64

2.24 (1.35-3.72)

383

19

1.20 (0.54-2.70)

384

18

1.37 (0.59-3.18)

386

16

1.96 (0.79-4.87)

Night sweats

No

272

31

1.00

285

18

1.00

288

15

1.00

293

10

1.00

Yes

392

72

1.42 (0.84-2.39)

444

20

0.40 (0.18-0.90)

448

16

0.66 (0.29-1.53)

450

14

0.82 (0.34-1.97)

Difficulty concentrating

No

268

34

1.00

282

20

1.00

292

10

1.00

293

9

1.00

Yes

396

69

1.51 (0.91-2.50)

447

18

0.41 (0.18-0.90)

444

21

1.84 (0.77-4.41)

450

15

1.17 (0.48-2.84)

Interrupted sleeping

No

146

18

1.00

154

10

1.00

151

13

1.00

157

7

1.00

Yes

518

85

1.49 (0.80-2.80)

575

28

0.67 (0.26-1.77)

585

18

0.28 (0.12-0.68)

586

17

0.54 (0.21-1.39)

Irritability or mood swingsb

No

270

24

1.00

283

11

1.00

281

13

1.00

282

12

1.00

Yes

393

79

2.19 (1.26-3.82)

445

27

1.20 (0.51-2.87)

454

18

0.79 (0.34-1.86)

460

12

0.59 (0.24-1.45)


aAdjusted for education, age at diagnosis, medical comorbidity, activity level within the past year of 30-month interview, a combined variable for menopause and hormone therapy, isoflavones from soy-containing foods. In addition, soy supplement, ginseng, flaxseed oil, black cohosh, yam, dong quai, red clover, licorice, alfalfa, DHEA, cat's claw, and other EBS use mutually adjusted. bExcluded one woman with missing information of irritability or mood swings.

Ma et al. BMC Complementary and Alternative Medicine 2011 11:109   doi:10.1186/1472-6882-11-109

Open Data