Female genital mutilation of a karyotypic male presenting as a female with delayed puberty

M Ellaithi^*¹^,2^,3 , T Nilsson^*⁴ , D Gisselsson^*⁴ , A Elagib⁵ , H Eltigani⁶ and I Fadl-Elmula⁷^,8

¹Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan

²International University of Africa, Faculty of Medicine and Health Sciences, Khartoum, Sudan

³The Orchids Society for Congenitally Malformed Children. Khartoum, Sudan

⁴Department of Clinical Genetics, Lund University, Lund, Sweden

⁵Tropical Medical Research Institute, Khartoum, Sudan

⁶Department of Anatomy, Faculty of Medicine, University of Khartoum, Khartoum, Sudan

⁷Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan

⁸Al Neelain Medical Centre, Al Neelain University, Khartoum, Sudan

author email corresponding author email* Contributed equally

BMC Women's Health 2006, 6:6doi:10.1186/1472-6874-6-6


Published:	29 March 2006

Abstract

Background

Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been discussed before.

Case presentation

The patient first presented as a female with delayed puberty. Hormonal analysis revealed a normal serum prolactin level of 215 Mu/L, a low FSH of 0.5 Mu/L, and a low LH of 1.1 Mu/L. Type IV FGM (Pharaonic circumcision) had been performed during childhood. Chromosomal analysis showed a 46, XY karyotype and ultrasonography verified a soft tissue structure in the position of the prostate.

Conclusion

FGM pose a threat to the diagnosis and management of children with abnormal genital development in the Sudan and similar societies.