Research article

Asymptomatic bacteriuria in type 2 Iranian diabetic women: a cross sectional study

Mohammad Ali Boroumand¹ , Leila Sam² , Seyed Hesameddin Abbasi^1,3 , Mojtaba Salarifar¹ , Ebrahim Kassaian¹ and Saeedeh Forghani⁴

¹  Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

²  Social Security Organization, Karaj, Iran

³  National Iranian Oil Company Central Hospital, Tehran, Iran

⁴  Razi Institute, Karaj, Iran

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BMC Women's Health 2006, 6:4doi:10.1186/1472-6874-6-4

Published:	23 February 2006

Abstract

Background

The risk of developing infection in diabetic patients is higher and urinary tract is the most common site for infection. Serious complications of urinary infection occur more commonly in diabetic patients. To study the prevalence and associates of asymptomatic bacteriuria (ASB) in women with type 2 diabetes mellitus in the Iranian population, this study was conducted.

Methods

Between February 10, 2004 and October 15, 2004; 202 nonpregnant diabetic (type 2) women (range: 31 to 78 years old) with no abnormalities of the urinary tract system were included in this clinic based study. We defined ASB as the presence of at least 10⁵ colony-forming units/ml of 1 or 2 bacterial species, in two separated cultures of clean-voided midstream urine. All the participants were free from any symptoms of urinary tract infection (UTI). Associates for developing bacteriuria was assessed and compared in participants with and without bacteriuria.

Results

In this study, the prevalence of ASB was 10.9% among diabetic women. E. coli was the most prevalent microorganism responsible for positive urine culture. Most of the isolated microorganisms were resistant to Co-trimoxazole, Nalidixic acid and Ciprofloxacin. Pyuria (P < 0.001) and glucosuria (P < 0.05) had a meaningful relationship with bacteriuria but no association was evident between age (P < 0.45), duration of diabetes (P < 0.09), macroalbuminuria (P < 0.10) and HbA_1c level (P < 0.75), and the presence of ASB.

Conclusion

The prevalence of ASB is higher in women with type 2 diabetes, for which pyuria and glucosuria can be considered as associates. Routine urine culture can be recommended for diabetic women even when there is no urinary symptom.