Table 6

Morphine equivalent median daily doses in subjects continuously exposed to opioids by time and by permanence in the cohort

Time period

Number of subjects who did not continue

Median dose in subjects who did not continue

Number of subjects who continued exposure

Median dose in subjects who continued exposure


Half year

166

56.25

453

45.0


> 6 months to 1 year

200

48.21

253

44.4


> 1 to 1.5 years

107

51.45

145

45.0


> 1.5 to 2 years

60

46.07

86

49.75


> 2 to 2.5 years

48

45.67

38

60.0


> 2.5 to 3 years

14

75.5

24

54.06


> 3 to 3. 5 years

5

60

19

52.2


> 3. 5 to 4 years

2

47.14

17

45.0


> 4 to 4.5 years

4

30.52

13

60.0


> 4.5 to 5 years

4

37.5

9

96.0


> 5 to 5.5 years

0

--

9

156.4


> 5.5 to 6 years

1

240.0

8

120.0


> 6 to 6.5 years

1

240.0

7

75.0


> 6.5 to 7 years

4

49.8

3

210.0


> 7 to 7.5 years

1

381.7

2

123.4


> 7.5 to 8 years

1

210.0

1

45.0


Median dose

56.25

45.0


Cepeda et al. BMC Palliative Care 2010 9:14   doi:10.1186/1472-684X-9-14

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