Table 1

Details of cases recalled by physicians where nebulised frusemide was used
Age Sex Primary diagnosis Main problem causing breathlessness Previous therapies for breathlessness Impression of clinical efficacy Comments
Case 1 70 Female NSCL cancer with COPD Bronchial obstruction Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics Possible improvement No comments provided
Case 2 78 Male Pulmonary oedema Cardiac failure Oxygen, Opioids, Benzodiazepines Unsure of any benefit No comments provided
Case 3 60 Female CRC, lung metastases, pleural effusion, lymphangitis Pleural effusion, lymphangitis Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Drainage of pleural effusion Possible improvement No comments provided
Case 4 84 Male Respiratory failure, History of AF & cardiomyopathy Pulmonary fibrosis and some mild LVF Oxygen, Opioids, Nebulised atrovent, Low dose midazolam Obvious improvement No comments provided
Case 5 70’s Male COPD, Lung cancer COPD, Lung metastases Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics Possible improvement No comments provided
Case 6 65 Male Not reported Not reported Oxygen, Opioids, Steroids, Benzodiazepines Possible improvement frusemide No comments provided
Case 7 60’s Female Stage IV NSCLC Cardiac failure Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics Possible improvement No comments provided
Case 8 37 Female Lung cancer Local disease, airway compromise, effusion Oxygen, Opioids, Steroids, Bronchodilators Obvious improvement She was quite anxious and benzo’s used helped significantly but further improvement seen after adding lasix as well
Case 9 72 Female Metastatic vulval cancer Pleural effusion Oxygen, Opioids, Steroids, Glycopyrolate Obvious improvement Within 20 minutes, patient came out of unconsciousness. I am considering using now as first line with atrovent when acute episode occurs after chronic control.
Case 10 70’s Male Respiratory failure End stage COPD Oxygen, Opioids, Steroids, Benzodiazepines, Bronchodilators, Antibiotics Obvious improvement Addition of nebulised frusemide improved difficult dyspnea, where all other modalities had been tried;

NSCL Non-small cell carcinoma of the lung; COPD Chronic obstructive pulmonary disease; CRC colorectal cancer; AF atrial fibrillation; IHD: Ischemic heart disease.

Newton et al.

Newton et al. BMC Palliative Care 2012 11:6   doi:10.1186/1472-684X-11-6

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