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Open Access Highly Accessed Review

Clinical aspects of palliative care in advanced Parkinson’s disease

Johan Lokk1 and Ahmad Delbari12*

Author affiliations

1 Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatric, Huddinge Hospital, R94, Karolinska Institute, Stockholm, Sweden, SE–141 86

2 Iranian Research Center on Healthy Aging, Sabzevar University of Medical Sciences, Sabzevar, Iran

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Citation and License

BMC Palliative Care 2012, 11:20  doi:10.1186/1472-684X-11-20

Published: 25 October 2012


Parkinson's disease (PD) is one of the most common neurodegenerative disorders of the elderly population. Few therapeutic options are available for patients with PD requiring palliative care. Treatment of the early stages of PD is entirely different from later stages. During the later stages, the palliative care model is introduced to provide the patient with comfort and support. Early palliative care in PD requires minimization of dyskinesias and decreasing occurrence of motor and non-motor off times in an effort to maximize independent motor function. In the later stages, the focus of treatment shifts to treating the predominant non-motor symptoms and having a more supportive and palliative nature. The purpose of this review is to provide a summary of the palliative care management issues and palliative care management options of end-stage PD patients.

Clinical aspects; End-stage; Palliative care; Parkinson’s disease