Table 4

Propensity score analysis results 2: Survival impact across quintiles based on the propensity to receive aggressive-approach chemotherapy within 14 days of death among chemotherapy recipients with metastatic non-small cell lung cancer, who survived at least 3 months after their cancer diagnosis (n = 3,534)

Analysis

Variables

HR

(95%CI)

P-value


Stratified analysis

Lowest quintile of PS*

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

1.32

(0.90, 1.92)

0.15

Second quintile of PS

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

1.30

(0.98, 1.72)

0.07

Third quintile of PS

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

1.22

(0.81, 1.84)

0.35

Fourth quintile of PS

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

1.21

(0.94, 1.56)

0.14

Highest quintile of PS

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

0.85

(0.68, 1.07)

0.16

Multiple Cox regression adjustment using the PS

Standard chemotherapy

1.00

-

-

Aggressive-approach chemotherapy

1.21

(1.00, 1.48)

0.05


Abbreviation: HR, hazard ratio; CI, confidence interval; PS, propensity score.

* Patients are least likely to receive "aggressive-approach chemotherapy within 14 days of death."

† Patients are most likely to receive "aggressive-approach chemotherapy within 14 days of death."

Saito et al. BMC Palliative Care 2011 10:14   doi:10.1186/1472-684X-10-14

Open Data