Table 2

Predisposing factors for oral cavity infection in febrile episodes of neutropenic and non- neutropenic patients in radiotherapy, chemotherapy and radio chemotherapy treated cases
Causative factors Group = 1 Group = II Group = III
ANC ANC ANC
<500 ≥500 <500 ≥500 <500 ≥500
Duration of neutropenia >7 4(6.55)  4(4.87) 4(5.06)  44(7.01) 4(4.34)  46(7.22)
    P = 0.72     P = .71     P = 0.52
Oral mucositis (grade 0) 3(4.91)  43(3.65) 2(2.53)  44(7.01) 5(5.43)  42(2.40)
    P = 0.70     P = .23     P = .44
Oral mucositis (grade 1) 4(6.55)  43(3.65) 3(3.79)  45(8.77) 7(7.60)  46(7.22)
    P = 0.45     P = 0.27     P = .84
Oral mucositis (grade 2) 5(8.19)  45(6.09) 4(5.06)  45(8.77) 9(9.78)  44(4.81)
    P = .74     P = 0.49     P = .33
Oral mucositis (grade 3) 8(13.11)  48(9.75) 19(24.05)  45(8.77) 11(11.95)  47(8.43)
    P = 0.71     P = 0.05*     P = .60
Oral mucositis (grade 4) 9(14.75)  425(30.48) 11(13.92)  413(22.80) 32(34.78)  412(14.45)
    P < .05*     P =0.26     P < .001***
Anemia 4(6.55)  43(3.65) 5(6.32)  43(5.26) 5(5.43)  44(4.81)
    P = .45     P = 1     P = 1
Central venous line present 6(9.83)  47(8.53) 9(11.39)  47(12.28) 7(7.60)  415(18.07)
    P = .97     P = .91     P = .06
Peripheral line present 5(8.19)  43(3.65) 7(8.86)  45(8.77) 4(4.34)  49(10.84)
    P = .28     P = 77     P = .17
Community acquired 6(9.83)  417(20.73) 6(7.59)  43(5.26) 3(3.26)  49(10.84)
    P = 0.12     P = .73     P = .09
Nosocomial acquired 7(11.47)  44(4.87) 9(11.39)  43(5.26) 5(5.43)  49(10.84)
    P = .20     P = .34     P = 0.29

Note: % had been shown in parenthesis, the value in table shows number of patients, ANC = absolute neutrophil count, ANC of < 500 neutrophil/micro L (neutropenic), ANC ≥ 500 neutrophil/micro L (non-neutropenic). P = Probability value with an ANC of <500 neutrophil/micro L (neutropenic) vs. those with ANC > 500 neutrophil/micro L (non-neutropenic). P < .05 * less significant, P < .01 ** significant, P < .001 *** highly Significant.

Panghal et al.

Panghal et al. BMC Oral Health 2012 12:22   doi:10.1186/1472-6831-12-22

Open Data