Table 5

Induction of apoptosis/necrosis in INS-1E-ZnT8-EGFP cells relative to INS-1E cells following cytokine exposure (n = 3).

IL-1β/12 h

IL-1β/24 h

IL-1β/36 h

Mix/12 h

Mix/24 h

Mix/36 h


Apoptosis

-

*4.1 +/- 0.21

*1.8 +/- 0.23

-

-

-

Necrosis

-

-

-

-

-

-


Data represent mean of two independent experiments. Fold changes between cell lines are indicated. (*) p < 0.05 in both experiments. Only significant changes are shown +/- SEM. Mix. is IL-1β+TNF-α+IFN-γ IL-1β.

Egefjord et al. BMC Endocrine Disorders 2009 9:7   doi:10.1186/1472-6823-9-7

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