Table 6

Sensitivity analyses results

Life expectancy (years)

Quality-adjusted life expectancy (QALY)

Immediate Initiation

Delayed Initiation

Difference

Immediate Initiation

Delayed Initiation

Difference

Base case

11.40 ± 0.25

10.78 ± 0.24

0.61

7.53 ± 0.17

7.19 ± 0.16

0.34

Initiation of insulin - 6 year delay

11.40 ± 0.25

10.83 ± 0.25

0.57

7.53 ± 0.17

7.20 ± 0.17

0.33

Initiation of insulin - 4 year delay

11.40 ± 0.25

10.91 ± 0.25

0.48

7.53 ± 0.17

7.25 ± 0.17

0.28

Higher HbA1c change

11.66 ± 0.27

10.85 ± 0.23

0.82

7.94 ± 0.18

7.31 ± 0.16

0.63

Lower HbA1c change

11.11 ± 0.24

10.74 ± 0.25

0.37

7.48 ± 0.17

7.23 ± 0.17

0.24

No disutility for hypoglycaemia

11.40 ± 0.25

10.78 ± 0.24

0.61

7.88 ± 0.17

7.34 ± 0.16

0.55

QALY -- quality-adjusted life expectancy; HbA1c -- glycosylated haemoglobin; discrepancies are due to rounding.

Goodall et al. BMC Endocrine Disorders 2009 9:19   doi:10.1186/1472-6823-9-19