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Open Access Highly Accessed Research article

Neurocognitive function in children with compensated hypothyroidism: lack of short term effects on or off thyroxin

Naghma J Aijaz, Evelyn M Flaherty, Thomas Preston, Stacey Storch Bracken, Andrew H Lane and Thomas A Wilson*

BMC Endocrine Disorders 2006, 6:2  doi:10.1186/1472-6823-6-2

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Doubts on statistical validity

Angelika Schaffrath Rosario   (2006-07-04 17:09)  Robert Koch-Institute, Berlin, Germany email

I wonder whether a study with 11 children in an age range of 9 years can give any reliable quantitative information on neurocognitive function. It's no wonder that there are no significant results with this small sample size. Also, there seems to be no clear design in this study.

Competing interests

None declared

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