|
Resting echocardiographic measurements |
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| Severe GHD (n = 38) |
Mild GHD (n = 16) |
Controls (n = 20) |
p-value |
|
|
|
||||
| M-mode and two-dimensional parameters |
||||
| LVEDD (mm) |
49.4 ± 5.8 |
49.1 ± 4.0 |
49.3 ± 4.0 |
NS |
| LVESD (mm) |
30.7 ± 4.5 |
29.4 ± 3.9 |
30.1 ± 3.5 |
NS |
| IVS (mm) |
9.8 ± 1.8 |
10.6 ± 1.4 |
10.0 ± 1.5 |
NS |
| PW (mm) |
7.8 ± 1.4 |
7.8 ± 1.3 |
8.4 ± 1.4 |
NS |
| RWT |
0.36 ± 0.05 |
0.38 ± 0.05 |
0.38 ± 0.06 |
NS |
| LVM (g) |
194.2 ± 62.6 |
197.8 ± 46.6 |
195.3 ± 44.5 |
NS |
| LVMi (g/m2) |
104.8 ± 27.6 |
109.1 ± 24.9 |
106.1 ± 22.7 |
NS |
| LVDV (ml) |
82.3 ± 20.7 |
77.2 ± 19.2 |
80.8 ± 15.5 |
NS |
| LVSV (ml) |
30.4 ± 9.2 |
27.4 ± 8.3 |
31.7 ± 6.6 |
NS |
| LA systolic area (cm2) |
16.8 ± 3.8 |
15.7 ± 2.5 |
16.7 ± 1.4 |
NS |
| RA systolic area (cm2) |
14.2 ± 2.9 |
13.6 ± 2.2 |
14.1 ± 1.3 |
NS |
| Pericardial adiposity |
26 (68.4%)* |
10 (71.4%)* |
4 (20%) |
<0.001 |
|
|
||||
| Left ventricular function |
||||
| EFS (%) |
39.0 ± 5.1 |
40.1 ± 5.5 |
38.8 ± 4.9 |
NS |
| MFS (%) |
18.6 ± 2.7 |
18.8 ± 1.8 |
18.1 ± 2.3 |
NS |
| LVEF (%) |
63.5 ± 5.8 |
63.6 ± 9.0 |
61.5 ± 5.3 |
NS |
| Mitral E/A velocity ratio |
1.24 ± 0.56 |
0.99 ± 0.27 |
1.18 ± 0.48 |
NS |
| E-dt |
175.5 ± 36.8 |
195.7 ± 53.2 |
173.7 ± 39.8 |
NS |
| PV S/D ratio |
1.1 ± 0.6 |
1.0 ± 0.5 |
1.3 ± 0.3 |
NS |
| PV A velocity |
28.9 ± 3.2 |
29.3 ± 5.2 |
27.3 ± 4.2 |
NS |
|
Values are mean ± SD. Scheffé test for comparison of individual groups: *p < 0.01 (groups A-B vs C). Legends: E/A, Early/late diastolic velocity at left ventricular (LV) inflow; E-dt, E-velocity deceleration time; EFS, Endocardial fractional shortening; IVS, Interventricular septal thickness; LA, Left atrium; LVDV, LV diastolic volume; LVEDD, LV end-systolic diameter; LVEF, LV ejection fraction; LVESD, LV end-systolic diameter; LVM/LVMi, absolute/indexed LV mass; LVSV, LV systolic volume; MFS, midwall fractional shortening; PV, Right superior pulmonary vein; PW, Posterior wall thickness; RA, Right atrium; RWT, Relative wall thickness; S/D, Systolic/Diastolic velocity. | ||||
de Gregorio et al. BMC Endocrine Disorders 2006 6:1 doi:10.1186/1472-6823-6-1 |
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