Table 5

The prevalence of hypothyroidism in the IFN-naïve and IFN-treated HCV patients compared with the general populations. The prevalence of elevated TSH levels in the various population groups include: Australia ~2.0% [17], the United States of America ~7.3% [18], Spain ~2.0% [18], Japan ~1.3% [18], Great Britain ~7.3% [18] and Italy ~1.7% [19]

Studies N = number of subjects
Prevalence of hypothyroidism (before IFN)
Prevalence of hypothyroidism (after IFN)

Marcellin et al. [5] N = 74
0
7.2
Preziati et al. [15] N = 78
0
22.8
Imigawa et al. [14] N = 58
0
3.4
Marazuela et al. [7] N = 207
4.7
2.8
This work N = 272
1.1%
7.5%
Baudin et al. [16] N = 68
0
7.3
Antonelli et al. [13] N = 630
13%
N/A

Tran et al. BMC Endocrine Disorders 2005 5:8   doi:10.1186/1472-6823-5-8