|
Data for hypothyroid patients receiving combination therapy for Hepatitis C infection |
|
| Number of subjects |
15 (9 treated for 48 weeks and 6 for 24 weeks) |
|
|
|
| Gender |
3 M : 12 F |
| Mean age |
44 ± 2 |
| Positive family history of thyroid disease (in first degree relatives) |
8/18 (44%) |
| Duration of IFN-α before thyroid disease developed (months) |
4.8 ± 1.2 |
| Mean TSH levels (mU/L) |
29.7 ± 8.8 |
| Mean fT4 levels (pmol/L) |
3.5 ± 0.9 |
| The presence of TPO-autoantibodies |
6/15 (40%) |
| Thyroxine requirement at the 12-month follow-up |
13/15 (87%) |
| PCR negativity at the end of treatment |
15/15 (100%) |
Tran et al. BMC Endocrine Disorders 2005 5:8 doi:10.1186/1472-6823-5-8 |
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