Table 1

Clinical and biological characteristics of study patients by IR
Characteristics Total patients Patients without IR (Group 1) Patients with IR (Group 2) P
N 89 30 (33.7) 59 (66.3)
Age (years)a 28 (22) 20.5 (13) 33 (25) 0.12
Males 51 (57.3) 14 (46.7) 37 (62.7) 0.14
BMI (kg/m2) 23.6 ± 3.9 22.6 ± 3.8 24.2 ± 3.8 0.3
Fasting glucose (mg/dl) 85.7 ± 13.7 82.3 ± 8.6 87.2 ± 15 0.12
Haemoglobin A1c (%) 4.85 ± 0.39 4.82 ± 0.25 4.86 ± 0.43 0.66
Hypertensionb 23 (25.8) 8 (26.7) 15 (25.4) 1.00
CD4 Tcell (cells/mm3)a 440 (402) 525 (470) 428 (370) 0.38
Patients with undetectable HIV viral load 65 (73) 20 (66.7) 45 (76.3) 0.33
Time on antiretroviral therapy (months)a 72.5 (95) 80 (120) 70.5 (95) 0.21
Time from HIV diagnosis (months)a 80.5 (83) 92 (96) 76 (64) 0.36
Current Protease Inhibitor treatment 65 (73) 23 (76.7) 42 (71.2) 0.58
Total cholesterol (mg/dl) 192 ± 38.4 181.9 ± 33 199.6 ± 39.9 0.04*
HDL cholesterol (mg/dl) 43.9 ± 12.4 42.9 ± 10.5 44.3 ± 13.3 0.53
LDL cholesterol (mg/dl) 111.87 ± 35.4 107.3 ± 32.7 114.1± 36.8 0.39
Triglycerides (mg/dl)a 166 (129) 151.5 (79) 181 (169) 0.04*
Dyslipidemiac 71 (79.8) 24 (80) 47 (79.7) 1.00
Hypertriglyceridemiad 54 (60.7) 16 (53.3) 38 (64.4) 0.36
Adiponectin (μg/mL)a 10.2 (12.5) 16 (28.8) 9.4 (10.7) 0.00*
Leptin (ng/mL)a 1.4 (3.6) 1.8 (2.9) 1.3 (4.1) 0.53
Resistin (ng/mL)a 5.5 (3.6) 5.2 (5.1) 5.7 (3.4) 0.63
TNF alfa (pg/mL)a 10.3 (15.1) 11.9 (16.2) 9.7 (15) 0.62
IL-6 (pg/mL)a 26.5 (10.3) 26.6 (23.1) 26.5 (8.4) 0.52

Data are shown as mean ± SD or number (percent).

a Results presented as median (interquartile range).

b Hypertension defined as blood pressure ≥130/≥85 mm Hg or antihypertensive medication.

c Dyslipidemia defined as elevation of one of the following: total cholesterol, LDL cholesterol, triglyceride serum concentrations or a decrease of HDL cholesterol.

d Hypertriglyceridemia defined as serum triglycerides ≥150 mg/dl.

* p<0.05 Group 1 vs. Group 2.

p values based on t-test for equality of means or Mann–Whitney test for continuous variables, Chi-square or Fisher’s exact test for categorical variables.

Arama et al.

Arama et al. BMC Endocrine Disorders 2013 13:4   doi:10.1186/1472-6823-13-4

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