Table 1

Characteristics of participants (median (IQ range)) by 90 minute MMT stimulated C-peptide (SCP, nmol/L) tertile
Tertile 1 (SCP ≤ 0.02,n = 27) Tertile 2 (SCP 0.02-0.8, n = 27) Tertile 3 (SCP ≥ 0.8, n = 26) p for trend
Age (years) 53 (42–62) 42 (30–64) 62 (37–71) 0.70
Age of diagnosis (years) 15 (8–23) 27 (21–44) 50 (28–59) 0.001
Duration of Diabetes 36 (26–45) 16 (3–21) 10 (2–15) 0.001
BMI 26 (23–28) 25 (23–29) 29 (25–37) 0.013
HbA1c (%) 7.9 (7.2-8.7) 7.7 (7.0-8.7) 7.9 (7.4-8.7) 0.57
HbA1c (mmol/mol) 63 (55–72) 60 (53–71) 63 (57–72) 0.57
Proportion Type 1 diabetes 93% 78% 31% 0.001
Fasting glucose (mmol/L) (Test 1) 10.1(7.9-12.9) 8.8 (6.4-12.8) 8.4 (7.0-10.5) 0.064
90 Minute post MMT C-peptide (nmol/L) 0.01 (0–0.01) 0.40 (0.23-0.65) 1.79 (1.12-2.30) 0.001
Prandial (rapid or soluble only*) insulin dose administered in MMT+I (units) 8 (5–10) 8 (6–12) 6.3 (4.8-12.3) 0.98
Total daily insulin dose (units) 46 (33–64) 42 (28–62) 45 (26–88) 0.90

Participants completing both MMT and MMTI only.

* where participant took a mixed morning insulin the rapid/soluble component was calculated.

Jones et al.

Jones et al. BMC Endocrine Disorders 2012 12:6   doi:10.1186/1472-6823-12-6

Open Data