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Open AccessResearch article

Universal partitioning of the hierarchical fold network of 50-residue segments in proteins

Jun-ichi Ito1 email, Yuki Sonobe2 email, Kazuyoshi Ikeda2,3,4 email, Kentaro Tomii3 email and Junichi Higo5 email

1Graduate School of Frontier Science, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan

2School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan

3Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), 2-42 Aomi, Koto-ku, Tokyo 135-0064, Japan

4PharmaDesign, Inc., 2-19-8 Hacchobori, Chuo-ku, Tokyo 104-0032, Japan

5The Center for Advanced Medical Engineering and Informatics, Osaka University, Open Laboratories for Advanced Bioscience and Biotechnology, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan

author email corresponding author email

BMC Structural Biology 2009, 9:34doi:10.1186/1472-6807-9-34

Published: 20 May 2009

Additional files

Additional file 1:

Supplementary Methods and Supplementary Results. There are three sections in the Supplementary Methods as follows: (1) The method of embedding the inter-cluster network into 3D space. (2) The definition of F-measure. (3) The coloring method for clusters in the 3D network. In the Supplementary Results, tertiary structures of fragments in the same cluster and those in the same community are discussed.

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