A structural model of R.Hpy188I with presumptive active site residues and the pair of cysteines (A) compared with alternative locations of the R84 residue transferred to positions 104 or 105, i.e. "computationally modeled" double mutants R84A/T104R (B) and R84A/N105R (C), respectively. The orientation of models is the same as in Figure 2.
Kaminska et al. BMC Structural Biology 2008 8:48 doi:10.1186/1472-6807-8-48