Revealing divergent evolution, identifying circular permutations and detecting active-sites by protein structure comparison

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Luonan Chen^*, Ling-Yun Wu, Yong Wang, Shihua Zhang and Xiang-Sun Zhang^*

* Corresponding authors: Luonan Chen chen@eic.osaka-sandai.ac.jp - Xiang-Sun Zhang zxs@amt.ac.cn

BMC Structural Biology 2006, 6:18 doi:10.1186/1472-6807-6-18