Figure 2.

Improvement of the solution structure of Byr2-RBD by an X-ray structure of the same molecule in complex with Ras. Upper Panel: (A) NMR structural bundle of Byr2-RBD [16] [PDB ID: 1I35] (B) X-ray structure of Byr2-RBD in complex with Ras [17] [PDB ID: 1K8R]. Note that residues 57 – 69 could not be traced in the electron density map. (C) Structural bundle created from the X-ray structure by using the published resolution of 0.3 nm and the B-factors. Lower panel: (D) 10 final refined structures of Byr2-RBD without and (E) with refinement in explicit solvent.