Functional asymmetry in the lysyl-tRNA synthetase explored by molecular dynamics, free energy calculations and experiment

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Samantha J Hughes^†, Julian A Tanner^†, Alison D Hindley, Andrew D Miller^* and Ian R Gould^*

* Corresponding authors: Andrew D Miller a.miller@ic.ac.uk - Ian R Gould i.gould@ic.ac.uk
† Equal contributors

BMC Structural Biology 2003, 3:5 doi:10.1186/1472-6807-3-5