Table 2

Inhibition of Jak enzyme activity
Kinase Compound 1 IC50(nM) Compound 2 IC50(nM)
Tyk2 6 ± 1 <3 (N = 4)
Jak1 5 ± 0.4 10 ± 0.1
Jak2 7 ± 2 4 ± 1
Jak3 42 ± 1 41 ± 3

Values are mean and standard errors.

For values below the sensitivity of the assay; the number of replicates is given.

Argiriadi et al.

Argiriadi et al. BMC Structural Biology 2012 12:22   doi:10.1186/1472-6807-12-22

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