Table 1

Alignment of HLA-DPA1 (α chain) and HLA-DPB1 (β chain) for the five most frequent DP proteins
AA Pos. 10 20 30 40 50 60
DPA1*01:03 IKADHVSTYA AFVQTHRPTG EFMFEFDEDE MFYVDLDKKE TVWHLEEFGQ AFSFEAQGGL
DPA1*02:01 ---------- ---------- ---------- Q--------- ---------R ----------
AA Pos. 70 80
DPA1*01:03 ANIAILNNNL NTLIQRSNHT
DPA1*02:01 ---------- ----------
AA Pos. 10 20 30 40 50 60
DPB1*01:01 RATPENYVYQ GRQECYAFNG TQRFLERYIY NREEYARFDS DVGEFRAVTE LGRPAAEYWN
DPB1*02:01 -------LF- ---------- ---------- ----LF---- ---------- ----DE----
DPB1*04:01 -------LF- ---------- ---------- -----F---- ---------- ----------
DPB1*04:02 -------LF- ---------- ---------- ----FV---- ---------- ----DE----
DPB1*05:01 -------LF- ---------- ---------- ----LV---- ---------- ----E-----
AA Pos. 70 80 90
DPB1*01:01 SQKDILEEKR AVPDRVCRHN YELDEAVTLQ
DPB1*02:01 --------E- -----M---- ---GGPM---
DPB1*04:01 ---------- -----M---- ---GGPM---
DPB1*04:02 ---------- -----M---- ---GGPM---
DPB1*05:01 ---------- -----M---- ----------

Patronov et al.

Patronov et al. BMC Structural Biology 2012 12:20   doi:10.1186/1472-6807-12-20

Open Data