Anchored clathrate water comparison. Waters located down the TQTA trough of PbINP (middle image) show near identical coordination as compared to the ice-like waters located down the TxT troughs of TmAFP (PDB 1EZG (chain A)) (right image) and sbwAFP (PDB 1M8N (chain A)) (left image) as revealed by X-ray crystallography. Hydrogen bonds are represented by black hatched lines, while oxygens are coloured red, and nitrogens dark blue. Waters are represented as red spheres.
Garnham et al. BMC Structural Biology 2011 11:36 doi:10.1186/1472-6807-11-36