Table 2

Comparison of our paths with intermediate structures of AdK

2RH5A

2RH5B

2RH5C

1E4Y

lRMSD (Å)

2.55

2.47

2.96

2.82

Closest conformation (percent)

86.89

82.46

73.4

4.95

The closest pathway index (normalized to 1–100) and the lRMSD of the closest point to each PDB structures shown in Table 1 are listed. 2RH5 is from a hyperthermophilic E. coli and 1E4Y is an AdK mutant having 99% sequence identity with 1AKE and 4AKE. The measurements were taken over an average of 20 runs

Haspel et al. BMC Structural Biology 2010 10(Suppl 1):S1   doi:10.1186/1472-6807-10-S1-S1