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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Matthew Kaiser PhD
Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure of biological macromolecules, including solving structures, structural and functional analyses, and computational modeling.
BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
BMC Structural Biology 2009, 9 :68
Biologically meaningful subfamilies of protein domains and functional residues can be predicted using an extension of the context-specific independence mixture clustering method which implements a partially-supervised learning approach to integrate experimental data.
BMC Structural Biology 2009, 9 :65
Changes in hydrophobic interactions at low temperatures favour a more open conformation of Esherichia coli tryptophanase, promoting release of the cofactor pyridoxal phosphate, which leads to dissociation of the tetramer into dimers.
BMC Structural Biology 2009, 9 :62
Comparing electron-ion interaction potentials of amino acids in pandemic H1N1 hemagglutinin against those of non-pandemic H1N1/N2 reveals four mutations that seem critical for increased interaction with human proteins, and three sites where mutations will probably increase human infectivity.
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Methodology article
Splitting statistical potentials into meaningful scoring functions: Testing the prediction of near-native structures from decoy conformations Patrick Aloy, Baldo Oliva BMC Structural Biology 2009, 9 :71 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The structural and functional determinants of the Axin and Dishevelled DIX domains Matthias T Ehebauer, Alfonso Martinez Arias BMC Structural Biology 2009, 9 :70 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Software
Interacting with the biomolecular solvent accessible surface via a haptic feedback device Matthew B Stocks, Steven Hayward, Stephen D Laycock BMC Structural Biology 2009, 9 :69 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Partially-supervised protein subclass discovery with simultaneous annotation of functional residues Benjamin Georgi, J BMC Structural Biology 2009, 9 :68 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103 Yan-Bin Teng, Yong-Liang Jiang, Yong-Xing He, Wei-Wei He, Fu-Ming Lian, Yuxing Chen, Cong-Zhao Zhou BMC Structural Biology 2009, 9 :67 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Machine learning integration for predicting the effect of single amino acid substitutions on protein stability Ay BMC Structural Biology 2009, 9 :66 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Conformational changes and loose packing promote E. coli Tryptophanase cold lability Anna Kogan, Garik Y Gdalevsky, Rivka Cohen-Luria, Yehuda Goldgur, Robert S Phillips, Abraham H Parola, Orna Almog BMC Structural Biology 2009, 9 :65 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Molecular models for intrastrand DNA G-quadruplexes Federico Fogolari, Haritha Haridas, Alessandra Corazza, Paolo Viglino, Davide Cor BMC Structural Biology 2009, 9 :64 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis Juha AE M BMC Structural Biology 2009, 9 :63 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of hemagglutinin structural domain and polymorphisms which may modulate swine H1N1 interactions with human receptor Veljko Veljkovic, Henry L Niman, Sanja Glisic, Nevena Veljkovic, Vladimir Perovic, Claude P Muller BMC Structural Biology 2009, 9 :62 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research
3PFDB - A database of Best Representative PSSM Profiles (BRPs) of Protein Families generated using a novel data mining approach Khader Shameer, Paramasivam Nagarajan, Kumar Gaurav, Ramanathan Sowdhamini BioData Mining 2009, 2 :8 (4 [Abstract ] [Provisional PDF ]
Research article
Ultrasound evidence of altered lumbar connective tissue structure in human subjects with chronic low back pain Helene M Langevin, Debbie Stevens-Tuttle, James R Fox, Gary J Badger, Nicole A Bouffard, Martin H Krag, Junru Wu, Sharon M Henry BMC Musculoskeletal Disorders 2009, 10 :151 (3 [Abstract ] [Provisional PDF ]
Research article
The zebrafish prospero homolog prox1 is required for mechanosensory hair cell differentiation and functionality in the lateral line.
Anna Pistocchi, Carmen G Feijoo, Pablo Cabrera, Eduardo J Villablanca, Miguel L Allende, Franco Cotelli BMC Developmental Biology 2009, 9 :58 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts Patricia W Kimani, Amey J Holmes, Ruth E Grossmann, Stephen E McGowan Respiratory Research 2009, 10 :119 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Purification and characterization of cysteine protease from germinating cotyledons of horse gram Rajeswari Jinka, Vadde Ramakrishna, Sridhar K Rao, Ramakrishna P Rao BMC Biochemistry 2009, 10 :28 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Short Report
The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase Valn BMC Research Notes 2009, 2 :227 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
RNA folding on the 3D triangular lattice Joel Gillespie, Martin Mayne, Minghui Jiang BMC Bioinformatics 2009, 10 :369 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
(PS)2 -v2: template-based protein structure prediction server Chih-Chieh Chen, Jenn-Kang Hwang, Jinn-Moon Yang BMC Bioinformatics 2009, 10 :366 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods Stefano Lise, Cedric Archambeau, Massimiliano Pontil, David T Jones BMC Bioinformatics 2009, 10 :365 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion Raimon Sabat Microbial Cell Factories 2009, 8 :56 (28 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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