Table 1

Vitellogenin transcriptional regulation in daf-2 pathway mutants

Genotype

Day

vit-2 #

vit-5 #

sod-3 #

Trials


Wildtype

1

1.0

1.0

1.0

17


Wildtype

2

0.54(0.20)

0.75 (0.30)

0.90 (0.31)

7 (6^)


Wildtype

4

0.39(0.35)

0.61 (0.59)

0.77 (0.54)

6 (5^)


Wildtype

6

0.19(0.16)

0.23(0.25)

1.1 (0.96)

13 (12^)


daf-2 (e1368)

1

1.9 (1.4)

1.5 (1.0)

9.9 (6.9)*

6


daf-2 (e1368)

2

0.74 (0.10)

0.55 (1.1)

5.7 (6.2)

3


daf-2 (e1368)

4

0.095

0.086

2.53

1


daf-2 (e1368)

6

0.10(0.08)

0.10(0.10)

4.5 (1.2)*

3


daf-2 (e1370)

1

1.6 (1.3)

0.86 (0.95)

20.4 (11.5)*

8


daf-2 (e1370)

2

0.64 (0.48)

0.16 (0.14)*

21.1 (4.9)*

3


daf-2 (e1370)

4

0.13(0.14)

0.04(0.05)

15.4 (14.5)

3


daf-2 (e1370)

6

0.05(0.03)*

0.03(0.03)*

21.7 (16.1)*

6


daf-16 (mgDf50);

daf-2(e1370)

1

2.1 (1.8)

1.8 (1.8)

1.05 (0.27)

6 (5^)


daf-16 (mgDf50);

daf-2(e1370)

2

0.29 (1.0)

0.40 (0.19)

0.56 (0.30)

2


daf-16 (mgDf50);

daf-2(e1370)

4

0.29 (0.43)

0.47 (0.61)

0.24 (0.10)

3


daf-16 (mgDf50);

daf-2(e1370)

6

0.28 (0.29)

0.35 (0.32)

0.34 (0.21)*

2


# mRNA levels relative to day 1 wildtype (SD).

Bold, p < 0.05 vs day 1, within genotype, T-test.

^ Trials in which sod-3 was measured.

* p < 0.05 vs wildtype, same day, T-test.

DePina et al. BMC Physiology 2011 11:11   doi:10.1186/1472-6793-11-11

Open Data