Figure 4.

Differential expression of genes related to peroxisomal lipid metabolism. We reanalyzed of Affymetrix GeneChip U133v2.0 expression profiles of human and chimpanzee tissues [51] using the masking strategy stated in the text. We used standard F-tests (FDR-adjusted using the Benjamini and Hochberg approach) to test for differences in the distributions by species for the 5 tissues. The fold change (FC) of human (Hsa) versus chimpanzee (Ptr) geometric mean gene expression scores are provided. Differentially expressed genes (≥1.2 FC in either direction with a Student's t-test, two-tailed P-value ≤0.05 after Bonferroni correction) for a given tissue are highlighted in red (higher in human) or green (higher in chimpanzee). Probe sets with (i) F-tests yielding a ≤5% FDR and (ii) differential expression in at least one tissue are shown. All data are provided in Additional File 3.

Watkins et al. BMC Physiology 2010 10:19   doi:10.1186/1472-6793-10-19
Download authors' original image