Table 5

GO categories with an over-representation of target proteins or their interacting partners

GO-ID

Category Description

Corrected p-value

Number of target proteins selected

Total number of proteins in category

Fraction of population as targets


Molecular function

51082

unfolded protein binding

3.26E-09

14

113

0.124

Biological process

6457

protein folding

1.65E-17

28

256

0.109

6915

apoptosis

4.63E-09

30

676

0.044

6986

response to unfolded protein

4.63E-09

11

61

0.18

Cellular component

5783

endoplasmic reticulum

2.83E-06

25

669

0.037


Fang et al. BMC Chemical Biology 2009 9:5   doi:10.1186/1472-6769-9-5

Open Data