Table 1

Functional and locational gene product categorization of Sortin2 hypersensitive ORFs.

Representation on dataset

Enrichment on dataset (-fold)

Sortin2

Genome

p-value


FUNCTIONAL CATEGORY


Cellular transport, transport facilities and transport routes

50.7

16.9

2.99 E-29

3.0

Protein fate (folding, modification, destination)

46.2

18.8

1.51 E-19

2.5

Biogenesis of cellular components

21.3

14

0.003

1.5

Interaction with the environment

12.9

7.55

0.004

1.7


LOCATIONAL CATEGORY


Endosome

16.4

0.94

6.2 E-35

17.5

Golgi

13.9

2.57

1.0 E-13

5.4

Transport vesicles

11.4

2.29

1.1 E-10

5.0

Punctate composite

8.95

2.29

6.3 E-07

3.9

Vacuole

16.4

4.63

1.1 E-10

3.5

ER

15.9

9.1

0.0011

1.8


Category representation of the abundance within Sortin2 hypersensitive (201 genes) and the Saccharomyces genome (6131 genes). P-value was calculated using hypergeometric distribution as statistical test. P-values < 0.0005 were considered as statistical significant.

Norambuena et al. BMC Chemical Biology 2008 8:1   doi:10.1186/1472-6769-8-1

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