Table 1

Functional and locational gene product categorization of Sortin2 hypersensitive ORFs.


Representation on dataset

Enrichment on dataset (-fold)

Sortin2
Genome
p-value


FUNCTIONAL CATEGORY





Cellular transport, transport facilities and transport routes
50.7
16.9
2.99 E-29
3.0
Protein fate (folding, modification, destination)
46.2
18.8
1.51 E-19
2.5
Biogenesis of cellular components
21.3
14
0.003
1.5
Interaction with the environment
12.9
7.55
0.004
1.7

LOCATIONAL CATEGORY





Endosome
16.4
0.94
6.2 E-35
17.5
Golgi
13.9
2.57
1.0 E-13
5.4
Transport vesicles
11.4
2.29
1.1 E-10
5.0
Punctate composite
8.95
2.29
6.3 E-07
3.9
Vacuole
16.4
4.63
1.1 E-10
3.5
ER
15.9
9.1
0.0011
1.8

Category representation of the abundance within Sortin2 hypersensitive (201 genes) and the Saccharomyces genome (6131 genes). P-value was calculated using hypergeometric distribution as statistical test. P-values < 0.0005 were considered as statistical significant.

Norambuena et al. BMC Chemical Biology 2008 8:1   doi:10.1186/1472-6769-8-1