Table 1

Cytotoxicity of compounds 5, 6, and doxorubicin against U937 leukemia cells in vitroa

Compd.

IC50 (nM)b


5

0.09

6

0.7

Doxorubicin

100


aCells were incubated with drugs for 48 h and the experiments were performed according to our previously published method [26]; bIC50 values are defined as the minimal drug concentration necessary to inhibit incorporation of [3H]thymidine by 50%, and are the averages of three experiments.

Wang et al. BMC Chemical Biology 2002 2:1   doi:10.1186/1472-6769-2-1

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