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Open Access Highly Accessed Research article

Chemical-genetic profile analysis of five inhibitory compounds in yeast

Md Alamgir12, Veronika Erukova12, Matthew Jessulat12, Ali Azizi3 and Ashkan Golshani12*

Author Affiliations

1 Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, K1 S 5B6, ON, Canada

2 Ottawa Institute of System Biology, University of Ottawa, 451 Smyth Road, Ottawa, K1 H 8M5, ON, Canada

3 Faculty of Medicine, University of Ottawa, 401 Smyth Road, Ottawa, K1 H 8L1, ON, Canada

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BMC Chemical Biology 2010, 10:6  doi:10.1186/1472-6769-10-6

Published: 6 August 2010

Additional files

Additional file 1:

Gene deletion sensitivities to different bioactive compounds.

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Additional file 2:

Descriptions of translation related genes that interact genetically with TAE2, TAE3 and TAE4 and produce a synthetic sick phenotype.

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Additional file 3:

Descriptions of translation related genes that are phenotypically suppressed by overexpression of TAE2 and TAE4 against treatment with neomycin and/or streptomycin.

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Open Data