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Open Access Highly Accessed Research article

NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

Charles Evans12, Katrina L Bogan34, Peng Song1, Charles F Burant2, Robert T Kennedy15* and Charles Brenner346*

Author Affiliations

1 Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA

2 Michigan Metabolomics and Obesity Center, University of Michigan, Ann Arbor, MI 48109, USA

3 Biochemistry Graduate Program, Dartmouth Medical School, Lebanon, NH 03756, USA

4 Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA

5 Department of Chemistry, University of Michigan, 930 N University Ave, Ann Arbor, MI 48109, USA

6 Department of Biochemistry, Carver College of Medicine, University of Iowa, 51 Newton Rd, 4-403 BSB, Iowa City, IA 52242, USA

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BMC Chemical Biology 2010, 10:2  doi:10.1186/1472-6769-10-2

Published: 22 February 2010

Additional files

Additional file 1:

Supplementary tables. Tables indicating observed change of standard metabolite peak areas under extraction conditions (Table S1) and ion suppression of standard metabolites in the presence of 13C-labeled yeast extract (Table S2)

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