r-GV immunizations elicit long lived antibody responses to the displayed SIV specific peptide inserts. Seventeen weeks after the second booster, mice were boosted again with homologous r-GV and then retained for 43 weeks. ELISA assessments of sera taken at week 43 demonstrate that notable titers remain at this very late time point: 1:160 for Rev; and for Tat and Nef1, the titers are ≥ 1:1,280. Note: for this graph the absorbance scale is 0.0 – 5.0 and note also that (*) indicates only one animal remained in the Rev group at 43 weeks.
Sremac and Stuart BMC Biotechnology 2008 8:9 doi:10.1186/1472-6750-8-9