Table 1

List of recombinant viruses and shuttle and BAC plasmid clones used for their generation

BAC-derived recombinant virus
ICP4 expression cassette on the vector
Shuttle vector
Integrated pM24-BAC-shuttle clone
Description

bM24-CMV

pFLS-CMV
pM24-BAC-CMV
The CMV promoter drives the ICP4 expression.
bM24-null

pFLS-ICP4
pM24-BAC-null
No active promoter drives the ICP4 expression.
bM24-empty
NONE
pFLS2
pM24-BAC-empty
No ICP4 CDS included on the vector. (A shuttle vector containing no ICP4 CDS was constructed)

bM24-BAC
N/A
N/A
pM24-BAC (Non-integrated prototype HSV-BAC)
Genetically identical to the prototype HSV-BAC virus M24-BAC

(N/A: not applicable)

Kuroda et al. BMC Biotechnology 2006 6:40   doi:10.1186/1472-6750-6-40