Table 2

Analysis of Variance (ANOVA) for quadratic model on the cell disruption capability and specific protein release activity of HBsAg from the result of CCD
Source DF Sum of Squares Mean Square F value p
Cell disruption capability
 Model 9 4946.52 549.61 11.53 0.0003
 A 1 24.63 24.63 0.52 0.4887
 B 1 68.42 68.42 1.44 0.2586
 C 1 3427.89 3427.89 71.9 < 0.0001
 A2 1 103.49 103.49 2.17 0.1714
 B2 1 307.23 307.23 6.44 0.0294
 C2 1 960.37 960.37 20.14 0.0012
 AB 1 54.44 54.44 1.14 0.3104
 AC 1 7.39 7.39 0.16 0.702
 BC 1 158.33 158.33 3.32 0.0984
 Residual 10 476.79 47.68
 Lack of Fit 5 453.91 90.78 19.85 0.0026
 Pure Error 5 22.87 4.57
Specific protein
 Model 9 1841 204.56 74.01 < 0.0001
 A 1 14.09 14.09 5.1 0.0476
 B 1 2.99 2.99 1.08 0.3228
 C 1 19.4 19.4 7.02 0.0243
 A2 1 537.7 537.7 194.56 < 0.0001
 B2 1 737.91 737.91 267 < 0.0001
 C2 1 872.46 872.46 315.68 < 0.0001
 AB 1 2.85E-04 2.85E-04 1.03E-04 0.9921
 AC 1 6.68 6.68 2.42 0.1511
 BC 1 2.85E-04 2.85E-04 1.03E-04 0.9921
 Residual 10 27.64 2.76
 Lack of Fit 5 19.77 3.95 2.51 0.1675
 Pure Error 5 7.87 1.57

Tam et al.

Tam et al. BMC Biotechnology 2012 12:70   doi:10.1186/1472-6750-12-70

Open Data