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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Biotechnology 2009, 9 :50
A creative application of high resolution melt curve analysis enables rapid visualization of the clonal diversity of phage selected from an antibody display library, providing a time and cost-efficient method of grouping identical clones prior to sequence analysis.
BMC Biotechnology 2009, 9 :48
Modified peroxisomes, decorated with golgi-derived v-SNARE molecules, may be used to re-route intracellular vesicle trafficking, enabling the secretion of intracellular proteins with potentially useful industrial biotechnology applications.
BMC Biotechnology 2009, 9 :22
The efficient production of biologically-active murine and viral Interleukin-10 (IL-10) in transgenic tobacco paves the way for oral administration of this anti-inflammatory cytokine in animal studies of autoimmune disease.
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Methodology article
Stable nuclear transformation of Gonium pectorale Kai Lerche, Armin Hallmann BMC Biotechnology 2009, 9 :64 (10 [Abstract ] [Provisional PDF ]
Research article
Production of N-acetyl-D-neuraminic Acid Using Two Sequential Enzymes Overexpressed as Double-Tagged Fusion Proteins Tzu-Hsien Wang, Ying-Yin Chen, Hsin-Hung Pan, Feng-Pao Wang, Chung-Hsien Cheng, Wen-Chien Lee BMC Biotechnology 2009, 9 :63 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
A further insight into the biosorption mechanism of Pt() by infrared spectrometry
Zhongyu Lin, Ru Xue, Yiwen Ye, Jianhong Zheng, Zhenling Xu BMC Biotechnology 2009, 9 :62 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies Oded Edelheit, Aaron Hanukoglu, Israel Hanukoglu BMC Biotechnology 2009, 9 :61 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity Thibaut Pelat, Michael Hust, Martha Hale, Marie-Paule Lefranc, Stefan Dubel, Philippe Thullier BMC Biotechnology 2009, 9 :60 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Novel sequential ChIP and simplified basic ChIP protocols for promoter co-occupancy and target gene identification in human embryonic stem cells Ricardo B Medeiros, Kate J Papenfuss, Brian Hoium, Kristen Coley, Joy Jadrich, Saik-Kia Goh, Anuratha Elayaperumal, Julio E Herrera, Ernesto Resnik, Hsiao-Tzu Ni BMC Biotechnology 2009, 9 :59 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Cell-free protein synthesis energized by slowly-metabolized maltodextrin Yiran Wang, Y-H. Percival Zhang BMC Biotechnology 2009, 9 :58 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Interfering ribonucleic acids that suppress expression of multiple unrelated genes Toby Passioura, Mary M Gozar, Amber Goodchild, Andrew King, Greg M Arndt, Michael Poidinger, Donald J Birkett, Laurent P Rivory BMC Biotechnology 2009, 9 :57 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Expression of endo-1, 4-beta-xylanase from Trichoderma reesei in Pichia pastoris and functional characterization of the produced enzyme Jun He, Bing Yu, Keying Zhang, Xuemei Ding, Daiwen Chen BMC Biotechnology 2009, 9 :56 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
High-titer preparation of Bombyx mori nucleopolyhedrovirus (BmNPV) displaying recombinant protein in silkworm larvae by size exclusion chromatography and its characterization Tatsuya Kato, Suganthi Lavender Manoha, Shigeyasu Tanaka, Enoch Y Park BMC Biotechnology 2009, 9 :55 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system Marco Girhard, Kazuhiro Machida, Masashi Itoh, Rolf D. Schmid, Akira Arisawa, Vlada B. Urlacher Microbial Cell Factories 2009, 8 :36 (10 [Abstract ] [Provisional PDF ]
Research
Morphogen-defined patterning of Escherichia coli enabled by an externally tunable band-pass filter Takayuki Sohka, Richard A Heins, Marc Ostermeier Journal of Biological Engineering 2009, 3 :10 (8 [Abstract ] [Provisional PDF ]
Methodology
Development of an automated speech recognition interface for personal emergency response systems Melinda Hamill, Vicky Young, Jennifer Boger, Alex Mihailidis Journal of NeuroEngineering and Rehabilitation 2009, 6 :26 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Assessment of the medicinal potentials of the methanol extracts of the leaves and stems of Buddleja saligna. Adeolu A Adedapo, Florence O Jimoh, Srinivas Vedic, Patrick J Masika, Anthony J Afolayan BMC Complementary and Alternative Medicine 2009, 9 :21 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Enzymatic hydrolysis of steam-pretreated lignocellulosic materials with Trichoderma atroviride enzymes produced in-house Krisztina Kovacs, Stefano Macrelli, George Szakacs, Guido Zacchi Biotechnology for Biofuels 2009, 2 :14 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Oncoproteomic profiling with antibody microarrays Mohamed SS Alhamdani, Christoph Schr Genome Med 2009, 1 :68 (6 [Abstract ] [Full text ] [PDF ]
Research article
Association between SNPs within candidate genes and compounds related to boar taint and reproduction Maren Moe, Sigbjorn Lien, Torunn Aasmundstad, Theo H.E. Meuwissen, Marianne H.S. Hansen, Christian Bendixen, Eli Grindflek BMC Genetics 2009, 10 :32 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Genome-wide scans using archived neonatal dried blood spot samples Mads V Hollegaard, Jonas Grauholm, Anders Borglum, Mette Nyegaard, Bent Norgaard-Pedersen, Torben Orntoft, Preben B Mortensen, Carsten Wiuf, Ole Mors, Michael Didriksen, Poul Thorsen, David M Hougaard BMC Genomics 2009, 10 :297 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
How can accelerated development of bioenergy contribute to the future UK energy mix? Insights from a MARKAL modelling exercise Donna Clarke, Sophie Jablonski, Brighid Moran, Gabrial Anandarajah, Gail Taylor Biotechnology for Biofuels 2009, 2 :13 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology
Development of a gene silencing DNA vector derived from a broad host range geminivirus Edward M Golenberg, D NOAH Sather, Leandria C Hancock, Kenneth J Buckley, Natalie M Villafranco, David M Bisaro Plant Methods 2009, 5 :9 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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