| | Current Opinion in Investigational Drugs, Volume 9 |
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:1-6 (7 January2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:7-10 (7January2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:11-20 (7January2008)
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Perseverance furthers? The role of the drug hunter in the postgenomic era
M Williams
Current Opinion in Investigational Drugs 2008, 9:21-27 (7January2008)
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Multi- and single-target agents for major psychiatric diseases: Therapeutic opportunities and challenges
EHF Wong, SS Nikam, M Shahid
Current Opinion in Investigational Drugs 2008, 9:28-36 (7January2008)
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Evolution of schizophrenia drugs: A focus on dopaminergic systems
SS Nikam, AK Awasthi
Current Opinion in Investigational Drugs 2008, 9:37-46 (7January2008)
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Selective nicotinic acetylcholine receptor agonists: Potential therapies for neuropsychiatric disorders with cognitive dysfunction
SL Cincotta, MS Yorek, TM Moschak, SR Lewis, JS Rodefer
Current Opinion in Investigational Drugs 2008, 9:47-56 (7January2008)
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The role of omega-3 fatty acids in mood disorders
LA Stahl, DP Begg, RS Weisinger, AJ Sinclair
Current Opinion in Investigational Drugs 2008, 9:57-64 (7January2008)
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Cannabinoids for the treatment of neuropathic pain: Clinical evidence
JC Ashton, ED Milligan
Current Opinion in Investigational Drugs 2008, 9:65-75 (7January2008)
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Multimodal analgesia: Its role in preventing postoperative pain
PF White
Current Opinion in Investigational Drugs 2008, 9:76-82 (7January2008)
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The role of tetrodotoxin-resistant sodium channels in pain states: Are they the next target for analgesic drugs?
I Silos-Santiago
Current Opinion in Investigational Drugs 2008, 9:83-89 (7January2008)
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Methylnaltrexone, a new peripheral   -receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effects
FM Reichle, PF Conzen
Current Opinion in Investigational Drugs 2008, 9:90-100 (7January2008)
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Seletracetam, a small molecule SV2A modulator for the treatment of epilepsy
JR Pollard
Current Opinion in Investigational Drugs 2008, 9:101-107 (7January2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:109-114 (1February2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:115-118 (1February2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:119-127 (1February2008)
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2007: A difficult year for HCV drug development
NA Meanwell, GW Koszalka
Current Opinion in Investigational Drugs 2008, 9:128-131 (1February2008)
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Novel inhibitors of human CMV
G Andrei, Clercq E De, R Snoeck
Current Opinion in Investigational Drugs 2008, 9:132-145 (1February2008)
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Norovirus gastroenteritis, increased understanding and
future antiviral options
M Tan, X Jiang
Current Opinion in Investigational Drugs 2008, 9:146-151 (1February2008)
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Microbicides for multidrug-resistant and multitropic HIV-1
OJ D'Cruz, FM Uckun
Current Opinion in Investigational Drugs 2008, 9:152-169 (1February2008)
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Novel treatment options for pediatric HIV infection
E Day, K Buckberry, MR Sharland, R Chakraborty
Current Opinion in Investigational Drugs 2008, 9:170-175 (1February2008)
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Multidrug-resistant Gram-negative bacterial infections:
The emerging threat and potential novel treatment
options
PI Vergidis, ME Falagas
Current Opinion in Investigational Drugs 2008, 9:176-183 (1February2008)
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Host and microbial cells as targets for armed antibodies in
the treatment of infectious diseases
E Dadachova, A Casadevall
Current Opinion in Investigational Drugs 2008, 9:184-188 (1February2008)
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PRO-2000, an antimicrobial gel for the potential
prevention of HIV infection
PS Fletcher, RJ Shattock
Current Opinion in Investigational Drugs 2008, 9:189-200 (1February2008)
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Ceftaroline fosamil, a cephalosporin derivative for the
potential treatment of MRSA infection
D Parish, N Scheinfeld
Current Opinion in Investigational Drugs 2008, 9:201-209 (1February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Iclaprim, a diaminopyrimidine dihydrofolate reductase
inhibitor for the potential treatment of antibiotic-resistant
staphylococcal infections
WJ Peppard, CD Schuenke
Current Opinion in Investigational Drugs 2008, 9:210-225 (1February2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, M Williams
Current Opinion in Investigational Drugs 2008, 9:227-232 (28February2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:233-235 (28February2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:236-244 (28February2008)
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Universal definition of acute myocardial infarction: The
role of cardiac troponins and the need for sensitive and
standardized assays
DC Gaze
Current Opinion in Investigational Drugs 2008, 9:245-246 (28February2008)
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Nuclear receptors as drug targets in obesity, dyslipidemia
and atherosclerosis
MK Hansen, TM Connolly
Current Opinion in Investigational Drugs 2008, 9:247-255 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Ultrasound carotid artery intima-media thickness
assessment for progression of atherosclerosis in lipid
intervention studies
TZ Naqvi
Current Opinion in Investigational Drugs 2008, 9:256-264 (28February2008)
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The anti-atherogenic potential of serum amyloid A
peptides
R Kisilevsky, S-P Tam, JB Ancsin
Current Opinion in Investigational Drugs 2008, 9:265-273 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Pharmacological therapies for raising HDL cholesterol
beyond synthetic small molecules
RA Garcia
Current Opinion in Investigational Drugs 2008, 9:274-280 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Phospholipids as cardiovascular therapeutics
NR Pandey, DL Sparks
Current Opinion in Investigational Drugs 2008, 9:281-285 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The renin-angiotensin system and therapeutic vaccines
for hypertension
F Zhu, Z Zhou, Y Liao
Current Opinion in Investigational Drugs 2008, 9:286-294 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
11beta-Hydroxysteroid dehydrogenase type 1 inhibitors for
metabolic syndrome
CG Schnackenberg
Current Opinion in Investigational Drugs 2008, 9:295-300 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Ilepatril (AVE-7688), a vasopeptidase inhibitor for the
treatment of hypertension
R Tabrizchi
Current Opinion in Investigational Drugs 2008, 9:301-309 (28February2008)
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Rhucin, a recombinant C1 inhibitor for the treatment of
hereditary angioedema and cerebral ischemia
H Longhurst
Current Opinion in Investigational Drugs 2008, 9:310-323 (28February2008)
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Prasugrel, a third generation thienopyridine and potent
platelet inhibitor
PA Gurbel, US Tantry
Current Opinion in Investigational Drugs 2008, 9:324-336 (28February2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, R Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:337-342 (4April2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:343-345 (4April2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:346-354 (4April2008)
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The success of bariatric surgery as treatment of type 2 diabetes should be a call to revitalize anti-obesity drug discovery and development
TJ Opgenorth
Current Opinion in Investigational Drugs 2008, 9:355-356 (4April2008)
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Recent considerations in the treatment of hypothyroidism
S Danzi, I Klein
Current Opinion in Investigational Drugs 2008, 9:357-362 (4April2008)
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New approaches to treatment of secondary hyperparathyroidism
F Locatelli, M Limardo, G Pontoriero
Current Opinion in Investigational Drugs 2008, 9:363-370 (4April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Sirtuins: Novel targets for metabolic disease
PJ Elliott, M Jirousek
Current Opinion in Investigational Drugs 2008, 9:371-378 (4April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Advances in glycogen phosphorylase inhibitor design
NG Oikonomakos, L Somsak
Current Opinion in Investigational Drugs 2008, 9:379-395 (4April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Growth hormone use in the treatment of idiopathic short stature
S Zucchini
Current Opinion in Investigational Drugs 2008, 9:396-401 (4April2008)
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Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes
CF Deacon
Current Opinion in Investigational Drugs 2008, 9:402-413 (4April2008)
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Cetilistat, a new lipase inhibitor for the treatment of obesity
R Padwal
Current Opinion in Investigational Drugs 2008, 9:414-421 (4April2008)
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Pegloticase, a polyethylene glycol conjugate of uricase for the potential intravenous treatment of gout
K Biggers, N Scheinfeld
Current Opinion in Investigational Drugs 2008, 9:422-429 (4April2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:431-438 (25April2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:439-441 (25April2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:442-450 (25April2008)
[Abstract] [Full text] [PDF]
Discovery and development of immunosuppressants for
transplantation: What are the lessons for specialty medicines?
RE Morris
Current Opinion in Investigational Drugs 2008, 9:451-454 (25April2008)
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Ceramide kinase: A potential anti-inflammatory target?
S Saxena, M Banerjee, RK Shirumalla, A Ray
Current Opinion in Investigational Drugs 2008, 9:455-462 (25April2008)
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PPARbeta/delta ligands as modulators of the inflammatory response
KS Kilgore, AN Billin
Current Opinion in Investigational Drugs 2008, 9:463-469 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Overcoming steroid insensitivity in smoking asthmatics
T Ahmad, PJ Barnes, IM Adcock
Current Opinion in Investigational Drugs 2008, 9:470-477 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Inflammation in Parkinson's disease: An update
PF Smith
Current Opinion in Investigational Drugs 2008, 9:478-484 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]
Vitamin D and innate immunity
M Hewison
Current Opinion in Investigational Drugs 2008, 9:485-490 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
DNAM-1: An amplifier of immune responses as a therapeutic target
in various disorders
M Elishmereni, I Bachelet, F Levi-Schaffer
Current Opinion in Investigational Drugs 2008, 9:491-496 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Seeking approval: Present and future therapies for pemphigus vulgaris
X Mao, AS Payne
Current Opinion in Investigational Drugs 2008, 9:497-504 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Herpesviruses and autoimmunity
DN Posnett
Current Opinion in Investigational Drugs 2008, 9:505-514 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
ABT-874, a fully human monoclonal anti-IL-12/IL-23 antibody for
the potential treatment of autoimmune diseases
C Ding, J Xu, J Li
Current Opinion in Investigational Drugs 2008, 9:515-522 (25April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
XToll, a recombinant chaperonin 10 as an anti-inflammatory
immunomodulator
W van Eden
Current Opinion in Investigational Drugs 2008, 9:523-533 (25April2008)
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Tovaxin, radiation-attenuated, patient-specific T-cells for the therapeutic vaccination of multiple sclerosis
N Hellings, P Stinissen
Current Opinion in Investigational Drugs 2008, 9:534-540 (25April2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:541-549 (28May2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:550-551 (28May2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:552-561 (28May2008)
[Abstract] [Full text] [PDF]
The role of senescence in the action of antitumor drugs
DA Gewirtz
Current Opinion in Investigational Drugs 2008, 9:562-564 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Immunotherapy of pancreatic carcinoma
A M rten, MW B chler
Current Opinion in Investigational Drugs 2008, 9:565-569 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Targeted therapy of renal cell cancer
PJ Wysocki, J Zolnierek, C Szczylik, A Mackiewicz
Current Opinion in Investigational Drugs 2008, 9:570-575 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]
Novel targets for the treatment and palliation of gastrointestinal neuroendocrine tumors
SN Pinchot, SC Pitt, RS Sippel, M Kunnimalaiyaan, H Chen
Current Opinion in Investigational Drugs 2008, 9:576-582 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
MicroRNAs and cancer epigenetics
M Fabbri
Current Opinion in Investigational Drugs 2008, 9:583-590 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
New combination therapies with cell-cycle agents
G Deep, R Agarwal
Current Opinion in Investigational Drugs 2008, 9:591-604 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Development of Src tyrosine kinase substrate binding site inhibitors
G Ye, R Tiwari, K Parang
Current Opinion in Investigational Drugs 2008, 9:605-613 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors
JA McCubrey, M Milella, A Tafuri, AM Martelli, P Lunghi, A Bonati, M Cervello, JT Lee, LS Steelman
Current Opinion in Investigational Drugs 2008, 9:614-630 (28May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Targeted therapies in Waldenstr  m macroglobulinemia
N Burwick, AM Roccaro, X Leleu, IM Ghobrial
Current Opinion in Investigational Drugs 2008, 9:631-637 (28May2008)
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AEG-35156, an antisense oligonucleotide against X-linked inhibitor of apoptosis for the potential treatment of cancer
I Tamm
Current Opinion in Investigational Drugs 2008, 9:638-646 (28May2008)
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SNS-595, a naphthyridine cell cycle inhibitor and stimulator of apoptosis for the treatment of cancers
DA Mills, HM Fekrazad, CF Verschraegen
Current Opinion in Investigational Drugs 2008, 9:647-657 (28May2008)
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Axitinib, a novel anti-angiogenic drug with promising activity in various solid tumors
TK Choueiri
Current Opinion in Investigational Drugs 2008, 9:658-671 (28May2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2008, 9:673-680 (1July2008)
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Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:681-683 (1July2008)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:684-693 (1July2008)
[Abstract] [Full text] [PDF]
Novel analgesic development: From target to patient or patient to target?
CJ Woolf
Current Opinion in Investigational Drugs 2008, 9:694-695 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Cognitive endpoints as disease biomarkers: Optimizing the congruency of preclinical models to the clinic
M Day, F Balci, HI Wan, GB Fox, JL Rutkowski, G Feuerstein
Current Opinion in Investigational Drugs 2008, 9:696-706 (1July2008)
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Linking calcium-channel isoforms to potential therapies
F Belardetti, GW Zamponi
Current Opinion in Investigational Drugs 2008, 9:707-715 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Homomeric and heteromeric P2X3 receptors in peripheral sensory neurons
J-D Brederson, MF Jarvis
Current Opinion in Investigational Drugs 2008, 9:716-725 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Neuroimmune interactions and pain: Focus on glial-modulating targets
EA Romero-Sandoval, RJ Horvath, JA DeLeo
Current Opinion in Investigational Drugs 2008, 9:726-734 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]
The emerging role of docosahexaenoic acid in neuroinflammation
SK Orr, RP Bazinet
Current Opinion in Investigational Drugs 2008, 9:735-743 (1July2008)
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PDEs as drug targets for CNS immune disorders
ALO Hebb, HA Robertson
Current Opinion in Investigational Drugs 2008, 9:744-753 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The role of sildenafil in the treatment of stroke
MM Bednar
Current Opinion in Investigational Drugs 2008, 9:754-759 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Estrogen receptor beta agonists in neurobehavioral investigations
E Choleris, AE Clipperton, A Phan, M Kavaliers
Current Opinion in Investigational Drugs 2008, 9:760-773 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Casopitant, a neurokinin-1 receptor antagonist with anti-emetic and antinausea activities
RM Navari
Current Opinion in Investigational Drugs 2008, 9:774-785 (1July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Morphine-6-glucuronide, an active morphine metabolite for the potential treatment of post-operative pain
GP Joshi
Current Opinion in Investigational Drugs 2008, 9:786-799 (1July2008)
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AL-108 and AL-208, formulations of the neuroprotective NAP fragment of activity-dependent neuroprotective protein, for cognitive disorders
H Geerts
Current Opinion in Investigational Drugs 2008, 9:800-811 (1July2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2008, 9:813-821 (25July2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:822-832 (25July2008)
[Abstract] [Full text] [PDF]
Respiration consists of two acts: First inspiration, then expect(or)ation  
T Jones
Current Opinion in Investigational Drugs 2008, 9:833-835 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Recombinant vaccines for influenza virus
RA Tripp, SM Tompkins
Current Opinion in Investigational Drugs 2008, 9:836-845 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
New developments in vaccines against respiratory viruses
M Wroblewska
Current Opinion in Investigational Drugs 2008, 9:846-855 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Signaling cascades as drug targets in model and pathogenic fungi
RJ Bastidas, JL Reedy, H Morales-Johansson, J Heitman, ME Cardenas
Current Opinion in Investigational Drugs 2008, 9:856-864 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
An update on the development of drugs against smallpox
Y-C Tse-Dinh
Current Opinion in Investigational Drugs 2008, 9:865-870 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Investigational antimicrobial drugs for bloodstream infections
IP Korbila, ME Falagas
Current Opinion in Investigational Drugs 2008, 9:871-878 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Daptomycin, a lipopeptide antibiotic in clinical practice
F Weis, A Beiras-Fernandez, G Schelling
Current Opinion in Investigational Drugs 2008, 9:879-884 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Raltegravir, an HIV-1 integrase inhibitor for HIV infection
C Cabrera
Current Opinion in Investigational Drugs 2008, 9:885-898 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Rilpivirine, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV infection
D Ripamonti, F Maggiolo
Current Opinion in Investigational Drugs 2008, 9:899-912 (25July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Tolevamer, an orally administered, toxin-binding polymer for Clostridium difficile-associated diarrhea
N Scheinfeld, K Biggers
Current Opinion in Investigational Drugs 2008, 9:913-924 (25July2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2008, 9:925-933 (22August2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:934-944 (22August2008)
[Abstract] [Full text] [PDF]
The development of novel anti-hyperlipidemic drugs: A tough business gets tougher
BR Krause
Current Opinion in Investigational Drugs 2008, 9:945-949 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
HDL: Still a target for new therapies?
SJ Nicholls
Current Opinion in Investigational Drugs 2008, 9:950-956 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Pulmonary arterial hypertension: On the way to a manageable disease
HAM Mucke
Current Opinion in Investigational Drugs 2008, 9:957-962 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Mineralocorticoid receptor antagonists and endothelial function
BA Maron, JA Leopold
Current Opinion in Investigational Drugs 2008, 9:963-969 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Endothelial dysfunction and chronic kidney disease:
Treatment options
JR Wu-Wong
Current Opinion in Investigational Drugs 2008, 9:970-982 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The effects of growth hormone and insulin-like growth factor-1 on
the aging cardiovascular system and its progenitor cells
JK Devin, PP Young
Current Opinion in Investigational Drugs 2008, 9:983-992 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Glucose-6-phosphate dehydrogenase: A novel therapeutic target in cardiovascular diseases
SA Gupte
Current Opinion in Investigational Drugs 2008, 9:993-1000 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Induced ion currents and the endothelin pathway as targets for
anti-arrhythmic agents
D Dai, Y Dai
Current Opinion in Investigational Drugs 2008, 9:1001-1008 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Hemospan: A hemoglobin-based oxygen carrier for potential use
as a blood substitute and for the potential treatment of critical limb
ischemia
Y Smani
Current Opinion in Investigational Drugs 2008, 9:1009-1019 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Apixaban, an oral, direct inhibitor of activated Factor Xa
E Shantsila, GYH Lip
Current Opinion in Investigational Drugs 2008, 9:1020-1033 (22August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Hematide, a novel peptide-based erythropoiesis-stimulating agent for
the treatment of anemia
IC Macdougall
Current Opinion in Investigational Drugs 2008, 9:1034-1046 (22August2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2008, 9:1049-1057 (24September2008)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:1058-1067 (24September2008)
[Abstract] [Full text] [PDF]
One genotype, many phenotypes
FF Bolander
Current Opinion in Investigational Drugs 2008, 9:1068-1069 (24September2008)
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Novel therapeutic agents targeting the glucocorticoid receptor for inflammation and cancer
P Sommer, DW Ray
Current Opinion in Investigational Drugs 2008, 9:1070-1077 (24September2008)
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Free fatty acid receptor family: Novel targets for the treatment of diabetes and dyslipidemia
J Bernard
Current Opinion in Investigational Drugs 2008, 9:1078-1083 (24September2008)
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The endoplasmic reticulum as a potential therapeutic target in nonalcoholic fatty liver disease
CL Gentile, MJ Pagliassotti
Current Opinion in Investigational Drugs 2008, 9:1084-1088 (24September2008)
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Advances in immunotherapy of castration-resistant prostate cancer: Bisphosphonates, phosphoantigens and more
F Dieli, N Caccamo, S Meraviglia
Current Opinion in Investigational Drugs 2008, 9:1089-1094 (24September2008)
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The anti-aging, metabolism potential of SIRT1
HS Ghosh
Current Opinion in Investigational Drugs 2008, 9:1095-1102 (24September2008)
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Application of ghrelin to gastrointestinal diseases
K Venkova, Meerveld B Greenwood-Van
Current Opinion in Investigational Drugs 2008, 9:1103-1107 (24September2008)
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Dexlansoprazole, a modified release formulation of an enantiomer of
lansoprazole, for the treatment of reflux esophagitis
KM Fock, TL Ang
Current Opinion in Investigational Drugs 2008, 9:1108-1115 (24September2008)
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Taranabant, a novel cannabinoid type 1 receptor inverse agonist
BA Fremming, ST Boyd
Current Opinion in Investigational Drugs 2008, 9:1116-1129 (24September2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens
Current Opinion in Investigational Drugs 2008, 9:1131-1137 (22October2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:1138-1148 (22October2008)
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Neuroinflammatory diseases and the importance of a healthy
blood-brain barrier
MJ Elices
Current Opinion in Investigational Drugs 2008, 9:1149-1150 (22October2008)
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NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs
JL Wallace, L Vong
Current Opinion in Investigational Drugs 2008, 9:1151-1156 (22October2008)
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Multiple indications for anti-inflammatory apolipoprotein
mimetic peptides
Lenten BJ Van, M Navab, GM Anantharamaiah, GM Buga, ST Reddy, AM Fogelman
Current Opinion in Investigational Drugs 2008, 9:1157-1162 (22October2008)
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Multi-target anti-inflammatory action of hepatocyte growth factor
R Gong
Current Opinion in Investigational Drugs 2008, 9:1163-1170 (22October2008)
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Bosentan for idiopathic pulmonary fibrosis
TE King
Current Opinion in Investigational Drugs 2008, 9:1171-1179 (22October2008)
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Therapeutics targeting IL-13 for the treatment of pulmonary inflammation and airway remodeling
K Blease
Current Opinion in Investigational Drugs 2008, 9:1180-1184 (22October2008)
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IgE and immunoglobulin free light chains in allergic disease: New therapeutic opportunities
FA Redegeld, CH Wortel
Current Opinion in Investigational Drugs 2008, 9:1185-1191 (22October2008)
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The role of sphingosine-1-phosphate and ceramide-1-phosphate in calcium homeostasis
V Hinkovska-Galcheva, SM VanWay, TP Shanley, RG Kunkel
Current Opinion in Investigational Drugs 2008, 9:1192-1205 (22October2008)
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Ocrelizumab, a humanized monoclonal antibody against CD20 for inflammatory disorders and B-cell malignancies
G Hutas
Current Opinion in Investigational Drugs 2008, 9:1206-1215 (22October2008)
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Atacicept, a homodimeric fusion protein for the potential treatment of diseases triggered by plasma cells
B Gatto
Current Opinion in Investigational Drugs 2008, 9:1216-1227 (22October2008)
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Talarozole, a selective inhibitor of P450-mediated all-trans retinoic acid for the treatment of psoriasis and acne
AN Geria, NS Scheinfeld
Current Opinion in Investigational Drugs 2008, 9:1228-1237 (22October2008)
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Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2008, 9:1239-1246 (25November2008)
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Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2008, 9:1247-1258 (25November2008)
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Not just nuclear proteins: 'Novel' autophagy cancer treatment targets - p53 and HMGB1
KM Livesey, D Tang, HJ Zeh, MT Lotze
Current Opinion in Investigational Drugs 2008, 9:1259-1263 (25November2008)
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HER-2-directed, small-molecule antagonists
M Arkin, MM Moasser
Current Opinion in Investigational Drugs 2008, 9:1264-1276 (25November2008)
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Folate-targeted drug strategies for the treatment of cancer
CP Leamon
Current Opinion in Investigational Drugs 2008, 9:1277-1286 (25November2008)
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Exploring multi-targeting strategies for the treatment of gliomas
AMP Omuro
Current Opinion in Investigational Drugs 2008, 9:1287-1295 (25November2008)
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Therapeutic prostate cancer vaccines: A review of the latest developments
M Mohebtash, RA Madan, JL Gulley, PM Arlen
Current Opinion in Investigational Drugs 2008, 9:1296-1301 (25November2008)
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Novel radioimmunopharmaceuticals for cancer imaging and therapy
RM Sharkey, DM Goldenberg
Current Opinion in Investigational Drugs 2008, 9:1302-1316 (25November2008)
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Targeted delivery of siRNA by nonviral vectors: Lessons learned from recent advances
S-D Li, L Huang
Current Opinion in Investigational Drugs 2008, 9:1317-1323 (25November2008)
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Pazopanib, a VEGF receptor tyrosine kinase inhibitor for cancer
therapy
B Sloan, NS Scheinfeld
Current Opinion in Investigational Drugs 2008, 9:1324-1335 (25November2008)
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BIBW-2992, a dual receptor tyrosine kinase inhibitor for the treatment
of solid tumors
N Minkovsky, A Berezov
Current Opinion in Investigational Drugs 2008, 9:1336-1346 (25November2008)
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Author Index 2008 - Volume 9
Current Opinion in Investigational Drugs 2008, 9:1347-1349 (25November2008)
[Abstract] [Full text] [PDF]
Contents Index 2008 - Volume 9
Current Opinion in Investigational Drugs 2008, 9:1350-1356 (25November2008)
[Abstract] [Full text] [PDF]
Subject Index 2008 - Volume 9
Current Opinion in Investigational Drugs 2008, 9:1357-1360 (25November2008)
[Abstract] [Full text] [PDF]
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