Current Opinion in Investigational Drugs
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Current Opinion in Investigational Drugs, Volume 4
Paper alert G Damia, M Daneshtalab, S Doggrell, RE Hurst Current Opinion in Investigational Drugs 2003, 4 :1-10 (24 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :11-14 (24 [Abstract ] [Full text ] [PDF ]
Patent alert D Banerjee, I Duncan, HAM Mucke, P Norman, N Press Current Opinion in Investigational Drugs 2003, 4 :15-25 (24 [Abstract ] [Full text ] [PDF ]
New developments in neuroscience M Williams Current Opinion in Investigational Drugs 2003, 4 :26-27 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Overview: The search for therapeutic strategies for cerebrovascular ischemia. K Kumar Current Opinion in Investigational Drugs 2003, 4 :28-30 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Genome-based drug discovery: Prioritizing disease-susceptibility/disease-associated genes as novel drug targets for schizophrenia. M Williams Current Opinion in Investigational Drugs 2003, 4 :31-36 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
New drug development for post-traumatic stress disorder. J Berlant Current Opinion in Investigational Drugs 2003, 4 :37-41 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
New hope in the treatment of painful symptoms in depression. M Briley Current Opinion in Investigational Drugs 2003, 4 :42-45 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Corticotropin-releasing hormone modulators and depression. F Holsboer Current Opinion in Investigational Drugs 2003, 4 :46-50 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Therapeutic options for Huntington's disease. YAM Grimbergen, RAC Roos Current Opinion in Investigational Drugs 2003, 4 :51-54 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Amyloid inhibitors and Alzheimer's disease. W Xia Current Opinion in Investigational Drugs 2003, 4 :55-59 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Tadalafil (Lilly ICOS). DP Rotella Current Opinion in Investigational Drugs 2003, 4 :60-65 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
RG-1068 (RepliGen). G Wheeler Current Opinion in Investigational Drugs 2003, 4 :66-71 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
DU-127090 (Solvay/H Lundbeck). W Wolf Current Opinion in Investigational Drugs 2003, 4 :72-76 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Sumanirole (Pharmacia). Paulis T de Current Opinion in Investigational Drugs 2003, 4 :77-82 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Nicaraven (Chugai). RR Leker Current Opinion in Investigational Drugs 2003, 4 :83-90 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Pagoclone (Indevus). A Bateson Current Opinion in Investigational Drugs 2003, 4 :91-95 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Erratum [Ijeoma A Azodo & Eli D Ehrenpreis: Alvimopan. Current Opinion in Investigational Drugs (2002) 3(10):1496-1501]. IA Azodo, ED Ehrenpreis Current Opinion in Investigational Drugs 2003, 4 :96 (24 [Abstract ] [Full text ] [PDF ]
Paper alert E Boven, G Damia, M Daneshtalab, RE Hurst, D Lane, A Palmer Current Opinion in Investigational Drugs 2003, 4 :97-107 (25 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :108-110 (25 [Abstract ] [Full text ] [PDF ]
Patent alert HAM Mucke, P Norman Current Opinion in Investigational Drugs 2003, 4 :111-114 (25 [Abstract ] [Full text ] [PDF ]
Metallo-beta-lactamase inhibitors: Could they give old antibacterials new life? JH Toney Current Opinion in Investigational Drugs 2003, 4 :115-116 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Antibacterial agents: Patent highlights July to December 2002 OA Phillips Current Opinion in Investigational Drugs 2003, 4 :117-127 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Overcoming multidrug resistance in Gram-negative bacteria K Poole Current Opinion in Investigational Drugs 2003, 4 :128-139 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Macrolide antibiotic interaction and resistance on the bacterial ribosome J Poehlsgaard, S Douthwaite Current Opinion in Investigational Drugs 2003, 4 :140-148 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Have the oxazolidinones lived up to their billing? Future perspectives for this antibacterial class AM Nilius Current Opinion in Investigational Drugs 2003, 4 :149-155 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Recent developments in mucosal immunomodulatory adjuvants AM Harandi, J Sanchez, K Eriksson, J Holmgren Current Opinion in Investigational Drugs 2003, 4 :156-161 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Targeting hepatitis C virus translation: Stopping HCV where it starts R Jubin Current Opinion in Investigational Drugs 2003, 4 :162-167 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Dengue vaccines: Preparing to roll back dengue M Jacobs, P Young Current Opinion in Investigational Drugs 2003, 4 :168-171 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Therapeutic options for diseases due to potential viral agents of bioterrorism MS Bronze, RA Greenfield Current Opinion in Investigational Drugs 2003, 4 :172-178 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Effect of tissue penetration on AmBisome efficacy J Adler-Moore, RT Proffitt Current Opinion in Investigational Drugs 2003, 4 :179-185 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Chronic pulmonary aspergillosis: Current classification and therapy GF Schiraldi, G Gramegna, Rosa C De, Cicero S Lo, P Capone, M Ferrarese, E Sbicego Current Opinion in Investigational Drugs 2003, 4 :186-191 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Teaching old drugs new tricks: Reincarnating immunosuppressants as antifungal drugs JR Blankenship, WJ Steinbach, JR Perfect, J Heitman Current Opinion in Investigational Drugs 2003, 4 :192-199 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
New cell wall targets for antifungal drugs CP Selitrennikoff, M Nakata Current Opinion in Investigational Drugs 2003, 4 :200-205 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
S-1360 (Shionogi-GlaxoSmithKline) A Billich Current Opinion in Investigational Drugs 2003, 4 :206-209 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
HPV vaccine (MedImmune/GlaxoSmithKline) A Billich Current Opinion in Investigational Drugs 2003, 4 :210-213 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Resiquimod (3M) T Jones Current Opinion in Investigational Drugs 2003, 4 :214-218 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Alovudine (Medivir) S Rusconi Current Opinion in Investigational Drugs 2003, 4 :219-223 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Balofloxacin (Choongwae) L Alksne Current Opinion in Investigational Drugs 2003, 4 :224-229 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert F Barone, M Daneshtalab, S Doggrell, RE Hurst, A Palmer, M Williams Current Opinion in Investigational Drugs 2003, 4 :231-243 (1 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :244-247 (1 [Abstract ] [Full text ] [PDF ]
Patent alert HAM Mucke, P Norman, N Press Current Opinion in Investigational Drugs 2003, 4 :248-261 (1 [Abstract ] [Full text ] [PDF ]
Metabolic profiling and biomarker discovery TJ Colatsky, S Sumner Current Opinion in Investigational Drugs 2003, 4 :262-263 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Approaches in anticoagulation: Rationales for target positioning HA Wieland, V Laux, D Kozian, M Lorenz Current Opinion in Investigational Drugs 2003, 4 :264-271 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Factor Xa inhibitors: Today and beyond JM Walenga, WP Jeske, D Hoppensteadt, J Fareed Current Opinion in Investigational Drugs 2003, 4 :272-281 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Targeting sources of superoxide and increasing nitric oxide bioavailability in hypertension AA Elmarakby, JM Williams, DM Pollock Current Opinion in Investigational Drugs 2003, 4 :282-290 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Therapeutic implications of cholesteryl ester transfer protein inhibitors in hyperlipidemia and low high-density lipoprotein-cholesterolemia A Inazu, H Mabuchi Current Opinion in Investigational Drugs 2003, 4 :291-297 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Current status of endothelin blockade for the treatment of cardiovascular and pulmonary vascular disease H Krum, D Liew Current Opinion in Investigational Drugs 2003, 4 :298-302 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
QT interval prolongation and cardiac risk assessment for novel drugs S Picard, P Lacroix Current Opinion in Investigational Drugs 2003, 4 :303-308 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Recent advances in the diagnosis and treatment of deep vein thrombosis: A regional consensus M Qari, H Abdel-Razeq, A Alzeer, H Alizadeh, J Kristensen, F Al-Sayegh, H Qutub, M Marashi, S Husted, S Mousa Current Opinion in Investigational Drugs 2003, 4 :309-315 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Eplerenone (Pharmacia) D Liew, J Martin, H Krum Current Opinion in Investigational Drugs 2003, 4 :316-322 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Tezosentan (Actelion/Genentech) E Rossetti, Servi S De Current Opinion in Investigational Drugs 2003, 4 :323-328 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
SLV-306 (Solvay) R Tabrizchi Current Opinion in Investigational Drugs 2003, 4 :329-332 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
MLN-519 (Millennium/PAION) M DiNapoli, F Papa Current Opinion in Investigational Drugs 2003, 4 :333-341 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
BO-653 (Chugai) CQ Meng Current Opinion in Investigational Drugs 2003, 4 :342-346 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Eflucimibe (Pierre Fabre/Eli Lilly) JR Burnett Current Opinion in Investigational Drugs 2003, 4 :347-351 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
RSD-1235 (Cardiome) GE Billman Current Opinion in Investigational Drugs 2003, 4 :352-354 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert G Damia, M Daneshtalab, S Doggrell, RE Hurst, A Palmer, M Williams Current Opinion in Investigational Drugs 2003, 4 :355-365 (6 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :366-368 (6 [Abstract ] [Full text ] [PDF ]
Patent alert I Duncan, HAM Mucke, P Norman, N Press Current Opinion in Investigational Drugs 2003, 4 :369-383 (6 [Abstract ] [Full text ] [PDF ]
Appetite suppressants: Problems and pitfalls of drug discovery. N Levens, Zuana O Della Current Opinion in Investigational Drugs 2003, 4 :384-385 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Prospects for obesity treatment: MCH receptor antagonists. CA Collins, PR Kym Current Opinion in Investigational Drugs 2003, 4 :386-394 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
The impact of statin treatment on diabetic patients. H Koshiyama Current Opinion in Investigational Drugs 2003, 4 :395-400 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Pharmacology of exenatide (synthetic exendin-4) for the treatment of type 2 diabetes. LL Nielsen, AD Baron Current Opinion in Investigational Drugs 2003, 4 :401-405 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Thiazolidinediones in diabetes: Current status and future outlook. HS Camp Current Opinion in Investigational Drugs 2003, 4 :406-411 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Dipeptidyl peptidase IV inhibitors for the treatment of impaired glucose tolerance and type 2 diabetes. PE Wiedeman, JM Trevillyan Current Opinion in Investigational Drugs 2003, 4 :412-420 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Pharmacological regulation of hepatic glucose production. JT Link Current Opinion in Investigational Drugs 2003, 4 :421-429 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Regulation of insulin receptor kinase activity by endosomal processes: Possible areas for therapeutic intervention. BI Posner Current Opinion in Investigational Drugs 2003, 4 :430-434 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Novel treatment options for overlapping yet distinct erectile dysfunction and andropause syndromes. RS Tan Current Opinion in Investigational Drugs 2003, 4 :435-438 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Hormone replacement therapy and health protection. LM Chiechi Current Opinion in Investigational Drugs 2003, 4 :439-443 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
MK-767 (Kyorin/Banyu/Merck). AC Calkin, MC Thomas, ME Cooper Current Opinion in Investigational Drugs 2003, 4 :444-448 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Insulin detemir (Novo Nordisk). D Barlocco Current Opinion in Investigational Drugs 2003, 4 :449-454 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
NN-414 (Novo Nordisk). JK Choi Current Opinion in Investigational Drugs 2003, 4 :455-458 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Exenatide (Amylin/Eli Lilly). N Giannoukakis Current Opinion in Investigational Drugs 2003, 4 :459-465 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
SomatoKine (Insmed). P Norman Current Opinion in Investigational Drugs 2003, 4 :466-471 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Miglustat (Oxford GlycoSciences/Actelion). RH Lachmann Current Opinion in Investigational Drugs 2003, 4 :472-479 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert F Barone, M Daneshtalab, S Doggrell, RE Hurst, A Palmer Current Opinion in Investigational Drugs 2003, 4 :481-495 (28 [Abstract ] [Full text ] [PDF ]
Patent selection HA Mucke Current Opinion in Investigational Drugs 2003, 4 :496-500 (28 [Abstract ] [Full text ] [PDF ]
Patent alert HA Mucke, P Norman Current Opinion in Investigational Drugs 2003, 4 :501-516 (28 [Abstract ] [Full text ] [PDF ]
After 100 years of aspirin, the anticytokine drugs offer a new approach to anti-inflammatory therapy. G Higgs Current Opinion in Investigational Drugs 2003, 4 :517-518 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Integrated assessment of preclinical data: Shifting high attrition rates to earlier phase drug development. C Korstanje Current Opinion in Investigational Drugs 2003, 4 :519-521 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Cellular targets of brain inflammation in stroke. HS Han, MA Yenari Current Opinion in Investigational Drugs 2003, 4 :522-529 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Transplantation: Tolerance. A Hutchings, JM Thomas Current Opinion in Investigational Drugs 2003, 4 :530-535 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Will non-steroid approaches to the treatment of inflammation replace our need for glucocorticoids? CJ Whelan Current Opinion in Investigational Drugs 2003, 4 :536-543 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Small molecule inhibitors of cell signaling: Novel future therapeutics for asthma and chronic obstructive pulmonary diseases K Blease, HK Raymon Current Opinion in Investigational Drugs 2003, 4 :544-551 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Antisense oligonucleotides to Syk kinase: A novel therapeutic approach for respiratory disorders. M Ulanova, L Puttagunta, MK Kim, AD Schreiber, AD Befus Current Opinion in Investigational Drugs 2003, 4 :552-555 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Anti-inflammatory activity of neutrophil elastase inhibitors. GM Tremblay, MF Janelle, Y Bourbonnais Current Opinion in Investigational Drugs 2003, 4 :556-565 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis. C Pargellis, J Regan Current Opinion in Investigational Drugs 2003, 4 :566-571 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
The role of IL-17 and family members in the pathogenesis of arthritis. E Lubberts Current Opinion in Investigational Drugs 2003, 4 :572-577 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Somatostatin analogs in rheumatoid arthritis and other inflammatory and immune-mediated conditions. D Paran, H Paran Current Opinion in Investigational Drugs 2003, 4 :578-582 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
PEG-sTNF-RI (Amgen) C Darlington Current Opinion in Investigational Drugs 2003, 4 :583-587 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
CDP-870 (Celltech/Pfizer) John S Rose, H Schooltink Current Opinion in Investigational Drugs 2003, 4 :588-592 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
IL-1 trap (Regeneron/Novartis) C Gabay Current Opinion in Investigational Drugs 2003, 4 :593-597 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
BMS-561392 (Bristol-Myers Squibb) M Grootveld, MF McDermott Current Opinion in Investigational Drugs 2003, 4 :598-602 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
AIC (Dynavax) B Bohle Current Opinion in Investigational Drugs 2003, 4 :603-607 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Alefacept (Biogen) AD Ormerod Current Opinion in Investigational Drugs 2003, 4 :608-614 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert G Damia, M Daneshtalab, Gasparo M de, RE Hurst, A Palmer, M Williams Current Opinion in Investigational Drugs 2003, 4 :615-629 (4 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :630-633 (4 [Abstract ] [Full text ] [PDF ]
Patent alert HAM Mucke, P Norman, C Whelan Current Opinion in Investigational Drugs 2003, 4 :634-648 (4 [Abstract ] [Full text ] [PDF ]
The critical need for cancer biometrics: Quantitative, reproducible measures of cancer to define response to therapy MT Lotze Current Opinion in Investigational Drugs 2003, 4 :649-651 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Anti-estrogens in the treatment of breast cancer: Current status and future directions S Barker Current Opinion in Investigational Drugs 2003, 4 :652-657 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Epidermal growth factor receptor inhibitors: An update on their development as cancer therapeutics L Seymour Current Opinion in Investigational Drugs 2003, 4 :658-666 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Angiogenesis inhibitors in cancer therapy K Dredge, AG Dalgleish, JB Marriott Current Opinion in Investigational Drugs 2003, 4 :667-674 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Telomerase inhibitors in cancer therapy: Current status and future directions CM Incles, CM Schultes, S Neidle Current Opinion in Investigational Drugs 2003, 4 :675-685 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
CpG oligodeoxynucleotides for immune stimulation in cancer immunotherapy B Jahrsdorfer, GJ Weiner Current Opinion in Investigational Drugs 2003, 4 :686-691 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Cancer therapeutic monoclonal antibodies targeting lymphocyte co-stimulatory pathways Y Zhu, L Chen Current Opinion in Investigational Drugs 2003, 4 :691-695 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Preclinical and clinical development of immunocytokines PM Sondel, JA Hank, J Gan, Z Neal, MR Albertini Current Opinion in Investigational Drugs 2003, 4 :696-700 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Polymer-protein and polymer-drug conjugates in cancer therapy M Thanou, R Duncan Current Opinion in Investigational Drugs 2003, 4 :701-709 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Vaccinating against GD3 ganglioside using BEC2 anti-idiotypic monoclonal antibody PB Chapman Current Opinion in Investigational Drugs 2003, 4 :710-715 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Developments in cancer vaccination J Lysaght, S Todryk Current Opinion in Investigational Drugs 2003, 4 :716-721 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Alphav Integrin inhibitors and cancer therapy GC Tucker Current Opinion in Investigational Drugs 2003, 4 :722-731 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
BMS-184476 (Bristol-Myers Squibb) I Ojima, R Geney Current Opinion in Investigational Drugs 2003, 4 :732-736 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
109881 (Aventis) I Ojima, R Geney Current Opinion in Investigational Drugs 2003, 4 :737-740 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Cilengitide (Merck) JW Smith Current Opinion in Investigational Drugs 2003, 4 :741-745 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
BMS-247550 (Bristol-Myers Squibb/GBF) N Lin, K Brakora, M Seiden Current Opinion in Investigational Drugs 2003, 4 :746-756 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
BAY-43-9006 (Bayer/Onyx) JT Lee, JA McCubrey Current Opinion in Investigational Drugs 2003, 4 :757-763 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Erratum Current Opinion in Investigational Drugs 2003, 4 :764 (4 [Abstract ] [Full text ] [PDF ]
Paper alert F Barone, G Damia, M Daneshtalab, S Doggrell, RE Hurst, A Palmer Current Opinion in Investigational Drugs 2003, 4 :765-779 (21 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :780-784 (21 [Abstract ] [Full text ] [PDF ]
Patent alert HAM Mucke, P Norman, N Press, C Whelan Current Opinion in Investigational Drugs 2003, 4 :785-802 (21 [Abstract ] [Full text ] [PDF ]
Serendipity in psychotropic drug research is alive and well, and working in clinical practice M Briley Current Opinion in Investigational Drugs 2003, 4 :803-804 (21 [Abstract ] [Full text ] [PDF ]
Prospects for novel antiepileptic drugs G Avanzini, S Francheschetti Current Opinion in Investigational Drugs 2003, 4 :805-814 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Psychosis of Parkinson's disease: Serotonin 2A receptor inverse agonists as potential therapeutics DM WEiner, KE Vanover, MR Brann, HY Meltzer, RE Davis Current Opinion in Investigational Drugs 2003, 4 :815-819 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Cholinergic therapies for Alzheimer's disease: Progress and prospects AM Palmer Current Opinion in Investigational Drugs 2003, 4 :820-825 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Therapeutic N-methyl-D-aspartate receptor antagonists: Will reality meet expectation? PF Smith Current Opinion in Investigational Drugs 2003, 4 :826-832 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
The P2X3 subunit: A molecular target in pain therapeutics RA North Current Opinion in Investigational Drugs 2003, 4 :833-840 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Vestibulotoxicity following aminoglycoside antibiotics and its prevention CL Darlington, PF Smith Current Opinion in Investigational Drugs 2003, 4 :841-846 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Update on pharmacological strategies for stroke: Prevention, acute intervention and regeneration JJ Legos, FC Barone Current Opinion in Investigational Drugs 2003, 4 :847-858 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Nemifitide (Innapharma) J Dingemanse Current Opinion in Investigational Drugs 2003, 4 :859-862 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
ONO-2506 (Ono) Paulis T de Current Opinion in Investigational Drugs 2003, 4 :863-867 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Ganstigmine (Chiesi) A Johnson Current Opinion in Investigational Drugs 2003, 4 :868-873 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Lerisetron (FAES) R Huckle Current Opinion in Investigational Drugs 2003, 4 :874-877 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
SLV-308 (Solvay) WA Wolf Current Opinion in Investigational Drugs 2003, 4 :878-883 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert G Damia, M Daneshtalab, S Doggrell, RE Hurst, D Lane, C Meng, A Palmer Current Opinion in Investigational Drugs 2003, 4 :883-893 (21 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :894-896 (21 [Abstract ] [Full text ] [PDF ]
Patent alert JF Barrett, HAM Mucke, N Press, C Whelan, P Norman Current Opinion in Investigational Drugs 2003, 4 :897-917 (21 [Abstract ] [Full text ] [PDF ]
Severe acute respiratory syndrome treatment: Present status and future strategy AC W Lau, LK Y So Current Opinion in Investigational Drugs 2003, 4 :918-920 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Overview - Granulocyte transfusions as treatment or prophylaxis for fungal infections? Burik JH van Current Opinion in Investigational Drugs 2003, 4 :921-925 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Antibacterial agents: Patent highlights January to June 2003 OA Phillips Current Opinion in Investigational Drugs 2003, 4 :926-936 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Bacterial RNase P as a potential target for novel anti-infectives PS Eder, C Hatfield, A Vioque, V Gopalan Current Opinion in Investigational Drugs 2003, 4 :937-943 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Gram-positive bacterial resistance: Future treatment options M Bassetti, G Melica, Biagio AD Di, R Rosso, G Gatti, D Bassetti Current Opinion in Investigational Drugs 2003, 4 :944-952 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Vaccines for Moraxella catarrhalis and non-typeable Haemophilus influenzae JC McMichael, BA Green Current Opinion in Investigational Drugs 2003, 4 :953-958 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Genetic systems of West Nile virus and their potential applications P-Y Shi Current Opinion in Investigational Drugs 2003, 4 :959-965 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
The effect of NNRTIs on HIV reverse transcriptase dimerization G Tachedjian, SP Goff Current Opinion in Investigational Drugs 2003, 4 :966-973 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Prevention of fungal infections in the immunocompromised host T Mahfouz, E Anaissie Current Opinion in Investigational Drugs 2003, 4 :974-990 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Pharmacokinetics and pharmacodynamics in the development of antifungal compounds D Andes Current Opinion in Investigational Drugs 2003, 4 :991-998 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
MBI-226 (Micrologix/Fujisawa) RE Isaacson Current Opinion in Investigational Drugs 2003, 4 :999-1003 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
SPD-754 (Shire) M Zhu Current Opinion in Investigational Drugs 2003, 4 :1004-1009 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Oral typhoid vaccine (Acambis/Berna) GW Witherell Current Opinion in Investigational Drugs 2003, 4 :1010-1018 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
ChimeriVax-JE (Acambis) T Jones Current Opinion in Investigational Drugs 2003, 4 :1019-1024 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert G Damia, M Daneshtalab, S Doggrell, RE Hurst, D Lane, C Meng, A Palmer, M Williams Current Opinion in Investigational Drugs 2003, 4 :1025-1036 (18 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :1037-1038 (18 [Abstract ] [Full text ] [PDF ]
Patent alert JF Barrett, P Norman, C Whelan Current Opinion in Investigational Drugs 2003, 4 :1039-1045 (18 [Abstract ] [Full text ] [PDF ]
Is there a 'treatment gap' in acute coronary syndromes? BR Krause, RS Newton Current Opinion in Investigational Drugs 2003, 4 :1046-1047 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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LXR agonists for the treatment of atherosclerosis M Jaye Current Opinion in Investigational Drugs 2003, 4 :1053-1058 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
p38 Mitogen-activated protein kinase inhibitors for the treatment of chronic cardiovascular disease TM Behr, M Berova, CP Doe, H Ju, CE Angermann, J Boehm, RN Willette Current Opinion in Investigational Drugs 2003, 4 :1059-1064 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Rho kinase inhibitors as potential therapeutic agents for cardiovascular diseases E Hu, D Lee Current Opinion in Investigational Drugs 2003, 4 :1065-1075 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Utility of endothelin-converting enzyme inhibitors for the treatment of cardiovascular diseases AY Jeng Current Opinion in Investigational Drugs 2003, 4 :1076-1081 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Prospects for prevention and treatment of vascular cognitive impairment Legge S Di, V Hachinski Current Opinion in Investigational Drugs 2003, 4 :1082-1087 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Diabetes mellitus: A cardiovascular disease R Candido, P Srivastava, ME Cooper, LM Burrell Current Opinion in Investigational Drugs 2003, 4 :1088-1094 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis A Miyazaki, M Sakai, Y Sakamoto, S Horiuchi Current Opinion in Investigational Drugs 2003, 4 :1095-1099 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis M Navab, GM Anantharamaiah, ST Reddy, Lenten BJ Van, G Hough, A Wagner, K Nakamura, DW Garber, G Datta, JP Segrest, S Hama, AM Fogelman Current Opinion in Investigational Drugs 2003, 4 :1100-1104 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
DX-9065a (Daiichi) B Kaiser Current Opinion in Investigational Drugs 2003, 4 :1105-1112 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Paper alert F Barone, G Damia, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, C Meng, M Williams Current Opinion in Investigational Drugs 2003, 4 :1141-1152 (17 [Abstract ] [Full text ] [PDF ]
Patent selection HAM Mucke Current Opinion in Investigational Drugs 2003, 4 :1153-1156 (17 [Abstract ] [Full text ] [PDF ]
Patent alert HAM Mucke, P Norman, C Whelan Current Opinion in Investigational Drugs 2003, 4 :1157-1163 (17 [Abstract ] [Full text ] [PDF ]
Clinical trials and anti-obesity agents: Expect the unexpected K Fujioka Current Opinion in Investigational Drugs 2003, 4 :1164-1165 (17 [Abstract ] [Full text ] [PDF ]
Novel regulation of insulin secretion: The role of mitochondria P Maechler Current Opinion in Investigational Drugs 2003, 4 :1166-1172 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Unmet medical needs and therapeutic goals in the treatment of type 2 diabetes L Bessac Current Opinion in Investigational Drugs 2003, 4 :1173-1178 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Protein tyrosine phosphatase 1B inhibitors for the treatment of type 2 diabetes and obesity: Recent advances EA Harley, N Levens Current Opinion in Investigational Drugs 2003, 4 :1179-1189 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
H3 Receptor antagonists/inverse agonists as anti-obesity agents AA Hancock Current Opinion in Investigational Drugs 2003, 4 :1190-1197 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Neuropeptide Y Y5 receptor antagonists as anti-obesity drugs NR Levens, Zuana O Della Current Opinion in Investigational Drugs 2003, 4 :1198-1204 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Therapeutic uses of dehydroepiandrosterone JP Hinson, A Brooke, PW Raven Current Opinion in Investigational Drugs 2003, 4 :1205-1208 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Use of estrogen antagonists and aromatase inhibitors in endometriosis P Vigano, S Mangioni, MP Odorizzi, A Chiodini, S Rocca, I Chiodo Current Opinion in Investigational Drugs 2003, 4 :1209-1212 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Delivery of testosterone replacement therapy A Hameed, T Brothwood, P Bouloux Current Opinion in Investigational Drugs 2003, 4 :1213-1219 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Controversy of hormone treatment and cardiovascular function: Need for strengthened collaborations between preclinical and clinical scientists VM Miller, LT Shuster, SN Hayes Current Opinion in Investigational Drugs 2003, 4 :1220-1232 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Fidarestat (Sanwa Kagaku/NC Curex/Sankyo) N Giannoukakis Current Opinion in Investigational Drugs 2003, 4 :1233-1239 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Paper alert M Daneshtalab, MJ Elices, C Meng, M Williams Current Opinion in Investigational Drugs 2003, 4 :1251-1259 (18 [Abstract ] [Full text ] [PDF ]
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Patent alert JF Barrett, HAM Mucke, P Norman, C Whelan Current Opinion in Investigational Drugs 2003, 4 :1262-1274 (18 [Abstract ] [Full text ] [PDF ]
T-cell depletion for transplant tolerance induction: Promises and hurdles FJ Dumont Current Opinion in Investigational Drugs 2003, 4 :1275-1278 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
The Th1 immune pathway as a therapeutic target in Crohn's disease G Bamias, K Sugawara, C Pagnini, F Cominelli Current Opinion in Investigational Drugs 2003, 4 :1279-1286 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Transplantation: Toxicokinetics and mechanisms of toxicity of cyclosporine and macrolides N Serkova, U Christians Current Opinion in Investigational Drugs 2003, 4 :1287-1296 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
JAK3 inhibition as a new concept for immune suppression DC Borie, MS Si, RE Morris, BA Reitz, PS Changelian Current Opinion in Investigational Drugs 2003, 4 :1297-1303 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Rationale for targeting interleukin-17 in the lungs A Linden Current Opinion in Investigational Drugs 2003, 4 :1304-1312 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Adenosine A2A receptor agonists as anti-inflammatory agents GW Sullivan Current Opinion in Investigational Drugs 2003, 4 :1313-1319 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Individual cytokines contributing to asthma pathophysiology: Valid targets for asthma therapy? KF Chung Current Opinion in Investigational Drugs 2003, 4 :1320-1326 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Leptin-based immune intervention: Current status and future directions Cava A La, G Matarese, FM Ebling, BH Hahn Current Opinion in Investigational Drugs 2003, 4 :1327-1332 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
The proteasome system and proteasome inhibitors in stroke: Controlling the inflammatory response Napoli M Di, F Papa Current Opinion in Investigational Drugs 2003, 4 :1333-1342 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Prostanoid receptors and the urogenital tract MD Breyer, RL Hebert, RM Breyer Current Opinion in Investigational Drugs 2003, 4 :1343-1353 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Natalizumab (Elan/Biogen) MJ Elices Current Opinion in Investigational Drugs 2003, 4 :1354-1362 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Semapimod (Cytokine) SV Sitaraman, M Hoteit, AT Gewirtz Current Opinion in Investigational Drugs 2003, 4 :1363-1368 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Onercept (Serono) SN Nikas, AA Drosos Current Opinion in Investigational Drugs 2003, 4 :1369-1376 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Diquafosol tetrasodium (Inspire/Allergan/Santen) J Fischberg Current Opinion in Investigational Drugs 2003, 4 :1377-1384 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Paper alert F Barone, M Daneshtalab, G Damia, S Doggrell, MJ Elices, RE Hurst, C Meng, M Williams Current Opinion in Investigational Drugs 2003, 4 :1385-1394 (18 [Abstract ] [Full text ] [PDF ]
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Patent alert HAM Mucke, P Norman, C Whelan Current Opinion in Investigational Drugs 2003, 4 :1398-1404 (18 [Abstract ] [Full text ] [PDF ]
Dealing with death: HMGB1 as a novel target for cancer therapy MT Lotze, RA DeMarco Current Opinion in Investigational Drugs 2003, 4 :1405-1409 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Strategies for treating cancers caused by multiple genome abnormalities: From concepts to cures? P Workman Current Opinion in Investigational Drugs 2003, 4 :1410-1415 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Multidrug resistance in cancer therapy: Role of the microenvironment CM Galmarini, FC Galamrini Current Opinion in Investigational Drugs 2003, 4 :1416-1421 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
HDAC inhibitors for the treatment of cancer JP Secrist, X Zhou, VM Richon Current Opinion in Investigational Drugs 2003, 4 :1422-1427 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Farnesyltransferase inhibitors as anticancer agents: Current status K Zhu, AD Hamilton, SM Sebti Current Opinion in Investigational Drugs 2003, 4 :1428-1435 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Raf pathway inhibitors in oncology G Bollag, S Freeman, JF Lyons, LE Post Current Opinion in Investigational Drugs 2003, 4 :1436-1441 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Decitabine: Development of a DNA methyltransferase inhibitor for hematological malignancies J Lyons, E Bayar, G Fine, M McCullar, R Rolens, J Rubinfeld, C Rosenfeld Current Opinion in Investigational Drugs 2003, 4 :1442-1450 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
ErbB family targeting JD Black, MG Brattain, SA Krishnamurthi, DM Dawson, JKV Willson Current Opinion in Investigational Drugs 2003, 4 :1451-1454 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
CKD-602 (Chong Kun Dang) M Crul Current Opinion in Investigational Drugs 2003, 4 :1455-1459 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
CMT-3 (CollaGenex) B Fingleton Current Opinion in Investigational Drugs 2003, 4 :1460-1467 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
ZD-6474 (AstraZeneca) D Bates Current Opinion in Investigational Drugs 2003, 4 :1468-1472 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
MEN-10755 (Menarini) K Jones Current Opinion in Investigational Drugs 2003, 4 :1473-1478 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Clofarabine (Bioenvision/ILEX) A Sternberg Current Opinion in Investigational Drugs 2003, 4 :1479-1487 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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