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Current Opinion in Investigational Drugs, Volume 2

 

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Paper alert
LJ Hofseth, D Witty, S Doggrell, Gasparo M de, D Lane, M Williams, ME Hurst, G Damia, M Daneshtalab, A Palmer, B Leonard
Current Opinion in Investigational Drugs 2001, 2:1-13 (5January2001)
[Abstract] [Full text] [PDF]


Patent alert
WM Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:14-34 (5January2001)
[Abstract] [Full text] [PDF]


The use of CpG DNA as a mucosal vaccine adjuvant
MJ McCluskie, RD Weeratna, PJ Payette, HL Davis
Current Opinion in Investigational Drugs 2001, 2:35-39 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Towards the development of vaccines against Helicobacter pylori: Status and issues
Giudice G Del
Current Opinion in Investigational Drugs 2001, 2:40-44 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview. Vaccines: Ideal drugs for the 21st century?
R Rappuoli, G Nabel
Current Opinion in Investigational Drugs 2001, 2:45-46 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Menjugate
DH Jones
Current Opinion in Investigational Drugs 2001, 2:47-49 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Tetracel
DH Jones
Current Opinion in Investigational Drugs 2001, 2:50-52 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Inhaled anticholinergic therapy: Applied pharmacology and interesting developments
TJ Witek, B Disse
Current Opinion in Investigational Drugs 2001, 2:53-58 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Neutrophil-derived elastases and their inhibitors: Potential role in the pathogenesis of lung disease
PT Reid, J-M Sallenave
Current Opinion in Investigational Drugs 2001, 2:59-67 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


ABT-761
DH Jones
Current Opinion in Investigational Drugs 2001, 2:68-71 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Inhibition of cardiac ATP-dependent potassium channels by sulfonylurea drugs
H Gein
Current Opinion in Investigational Drugs 2001, 2:72-80 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Therapy of heart failure
T Ecder, D Korular, AK Gurevich, HD Weinberger, RW Schrier
Current Opinion in Investigational Drugs 2001, 2:81-86 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


New antiarrhythmic agents for atrial fibrillation
DSG Conway, GYH Lip
Current Opinion in Investigational Drugs 2001, 2:87-92 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


KCB-328
G Billman
Current Opinion in Investigational Drugs 2001, 2:93-96 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Tedisamil
NA Flores
Current Opinion in Investigational Drugs 2001, 2:97-103 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The therapeutic potential of 5-HT6 receptor antagonists
C Reavill, DC Rogers
Current Opinion in Investigational Drugs 2001, 2:104-109 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cost effectiveness of the newer atypical antipsychotics: A review of the pharmacoeconomic research evidence
DA Revicki
Current Opinion in Investigational Drugs 2001, 2:110-117 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


SB-271046
Hidalgo MJ Miguel
Current Opinion in Investigational Drugs 2001, 2:118-122 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


M-100907
Paulis T de
Current Opinion in Investigational Drugs 2001, 2:123-132 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview. Humoral and cellular immune responses: Independent forces or collaborators in the fight against cancer?
RT Reilly, LA Emens, EM Jaffee
Current Opinion in Investigational Drugs 2001, 2:133-135 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Endothelial monocyte activating polypeptide II (EMAP II) enhances the effect of TNF on tumor-associated vasculature
ML Kayton, SK Libutti
Current Opinion in Investigational Drugs 2001, 2:136-138 (5January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Alemtuzumab
FJ Dumont
Current Opinion in Investigational Drugs 2001, 2:139-160 (8January2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, T Jones, S Doggrell, Gasparo M de, D Lane, M Williams, E Boven, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:161-172 (13February2001)
[Abstract] [Full text] [PDF]


Patent alert
OA Phillips, WM Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:173-197 (13February2001)
[Abstract] [Full text] [PDF]


Preclinical candidates and targets for tuberculosis therapy
III CE Barry
Current Opinion in Investigational Drugs 2001, 2:198-201 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


MEN-10700 (Menarini)
N Jiraskova
Current Opinion in Investigational Drugs 2001, 2:202-204 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Anti-MRSA cephalosporins (Bristol-Myers Squibb)
AP Johnson
Current Opinion in Investigational Drugs 2001, 2:205-208 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


RWJ-333441 (Microcide/RW Johnson)
N Jiraskova
Current Opinion in Investigational Drugs 2001, 2:209-211 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


MC-207110 (Daiichi Seiyaku/Microcide Pharmaceuticals)
JF Barrett
Current Opinion in Investigational Drugs 2001, 2:212-215 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Etanercept (Immunex).
RL Yung
Current Opinion in Investigational Drugs 2001, 2:216-221 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Leflunomide (Aventis Pharma).
MJ Kaplan
Current Opinion in Investigational Drugs 2001, 2:222-230 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


GL-701 (Genelabs).
P Norman
Current Opinion in Investigational Drugs 2001, 2:231-236 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Therapeutic approaches to childhood acquired aplastic anemia.
K Sugita
Current Opinion in Investigational Drugs 2001, 2:237-243 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Basic and clinical aspects of platelet integrin alphallbbeta3 receptor antagonists in acute coronary syndromes.
JA Goudevenos, AD Tselepis
Current Opinion in Investigational Drugs 2001, 2:244-249 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cangrelor (AstraZeneca).
SC Chattaraj
Current Opinion in Investigational Drugs 2001, 2:250-255 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Where are all the novel antidepressants?
E Richelson
Current Opinion in Investigational Drugs 2001, 2:256-258 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Drug mechanisms in anxiety.
M Bourin, M Hascoet
Current Opinion in Investigational Drugs 2001, 2:259-265 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Siramesine (H Lundbeck).
C Heading
Current Opinion in Investigational Drugs 2001, 2:266-270 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


(S)-Zopiclone (Sepracor).
V Georgiev
Current Opinion in Investigational Drugs 2001, 2:271-273 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


CRF antagonists (DuPont).
A Preti
Current Opinion in Investigational Drugs 2001, 2:274-279 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Receptor tyrosine kinase inhibitors.
P Haluska, AA Adjei
Current Opinion in Investigational Drugs 2001, 2:280-286 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


UCN-01 (Kyowa Hakko Kogyo Co).
K Grosios
Current Opinion in Investigational Drugs 2001, 2:287-297 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


OSI-774 (Pfizer).
P Norman
Current Opinion in Investigational Drugs 2001, 2:298-304 (13February2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, S Doggrell, D Lane, M Gasparo, F Barone, P Smith, B Leonard, G Damia, LJ Hofseth, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:305-319 (16March2001)
[Abstract] [Full text] [PDF]


Patent alert
W Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:320-334 (16March2001)
[Abstract] [Full text] [PDF]


Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: Is it all figured out?
LK Naeger, MD Miller
Current Opinion in Investigational Drugs 2001, 2:335-339 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMS-232632 Novartis/Bristol-Myers Squibb.
G Witherell
Current Opinion in Investigational Drugs 2001, 2:340-347 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


DAPD Emory University/Triangle Pharmaceuticals/Abbott Laboratories.
AH Corbett, JC Rublein
Current Opinion in Investigational Drugs 2001, 2:348-353 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


TAK-779 Takeda.
JA Est
Current Opinion in Investigational Drugs 2001, 2:354-356 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Treatment of transplant rejection: Are the traditional immunosuppressants good enough?
FJ Dumont
Current Opinion in Investigational Drugs 2001, 2:357-363 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


TP-10 AVANT Immunotherapeutics.
P Rioux
Current Opinion in Investigational Drugs 2001, 2:364-371 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Tresperimus Laboratoires Fournier.
MJ Elices
Current Opinion in Investigational Drugs 2001, 2:372-374 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Reverse cholesterol transport and future pharmacological approaches to the treatment of atherosclerosis.
BR Krause, BJ Auerbach
Current Opinion in Investigational Drugs 2001, 2:375-381 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


A clinical focus on statins.
J Auer, B Eber
Current Opinion in Investigational Drugs 2001, 2:382-388 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Ezetimibe Schering-Plough.
CQ Meng
Current Opinion in Investigational Drugs 2001, 2:389-392 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


S-8921 Shionogi.
ML Booker
Current Opinion in Investigational Drugs 2001, 2:393-395 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Differential gene expression - how to find new analgesic targets.
K Befort, M Costigan, CJ Woolf
Current Opinion in Investigational Drugs 2001, 2:396-398 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cannabinoids and pain.
ASC Rice
Current Opinion in Investigational Drugs 2001, 2:399-414 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Donitriptan Pierre Fabre.
M Dukat
Current Opinion in Investigational Drugs 2001, 2:415-418 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


MT-500 POZEN.
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:419-421 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Recent success with the tyrosine kinase inhibitor STI-571 - lessons for targeted therapy of cancer.
NP Shah, CL Sawyers
Current Opinion in Investigational Drugs 2001, 2:422-423 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


CT-2584 Cell Therapeutics.
RD Bonfil
Current Opinion in Investigational Drugs 2001, 2:424-427 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ZD-1839 AstraZeneca.
P Norman
Current Opinion in Investigational Drugs 2001, 2:428-435 (16March2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Editorial: Genomics, proteomics and gnomics
M Williams
Current Opinion in Investigational Drugs 2001, 2:437-439 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Paper alert
D Witty, T Jones, Gasparo M de, M Williams, B Leonard, P Smith, E Boven, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:440-446 (6April2001)
[Abstract] [Full text] [PDF]


Patent selection
M Mucke
Current Opinion in Investigational Drugs 2001, 2:447-450 (6April2001)
[Abstract] [Full text] [PDF]


Patent alert
OA Phillips, WM Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:451-467 (6April2001)
[Abstract] [Full text] [PDF]


Overview: Hitting a new target with echinocandins. Why chase something else?
JR Graybill
Current Opinion in Investigational Drugs 2001, 2:468-471 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Antifungal antibodies: A new approach to the treatment of systemic candidiasis
R Matthews, J Burnie
Current Opinion in Investigational Drugs 2001, 2:472-476 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Killer anti-idiotypes in the control of fungal infections
W Magliani, C Stefania, S Arseni, R Frazzi, A Salati, L Polonelli
Current Opinion in Investigational Drugs 2001, 2:477-479 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Nystatin LF (Aronex/Abbott)
S Arikan, JH Rex
Current Opinion in Investigational Drugs 2001, 2:480-487 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


A novel heparin-coated hydrophilic preparation of amphotericin B Hydrosomes
KV Clemons, DF Ranney, DA Stevens
Current Opinion in Investigational Drugs 2001, 2:480-487 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Inflammatory mediators as therapeutic targets in acute pancreatitis
M Bhatia, JP Neoptolemos, J Slavin
Current Opinion in Investigational Drugs 2001, 2:496-501 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


LDP-02 (Millennium)
JK Marshall
Current Opinion in Investigational Drugs 2001, 2:502-504 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ALX-0600 (NPS Allelix Corp)
DL Sigalet
Current Opinion in Investigational Drugs 2001, 2:505-509 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


IS-741 (Ishihara Sangyo)
C Bassi
Current Opinion in Investigational Drugs 2001, 2:510-512 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Endothelin antagonists in the treatment of renal failure.
DM Pollock
Current Opinion in Investigational Drugs 2001, 2:513-520 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Eplerenone (GD Searle)
J Martin, H Krum
Current Opinion in Investigational Drugs 2001, 2:521-524 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Lixivaptan (American Home Products)
A Martinez-Castelao
Current Opinion in Investigational Drugs 2001, 2:525-530 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Sitaxsentan (ICOS-Texas Biotechnology)
JR Wu-Wong
Current Opinion in Investigational Drugs 2001, 2:531-536 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Corticotropin releasing factor antagonists - the new anti-anxiety magic bullets?
WW Blessing
Current Opinion in Investigational Drugs 2001, 2:537-538 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


5-Hydroxytryptamine and the gastrointestinal migrating motor complex
MA Plaza
Current Opinion in Investigational Drugs 2001, 2:539-544 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Aviptadil (Senetek)
GBJM Keijzers
Current Opinion in Investigational Drugs 2001, 2:545-549 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Alibra (VIVUS)
AA Qureshi
Current Opinion in Investigational Drugs 2001, 2:550-554 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


GM-611 (Chugai Pharmaceutical)
TL Peeters
Current Opinion in Investigational Drugs 2001, 2:555-557 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Application of PNA and LNA oligomers to chemotherapy
AN Elayadi, DR Corey
Current Opinion in Investigational Drugs 2001, 2:558-561 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pharmacokinetics of phosphorothioate antisense oligodeoxynucleotides
RS Geary, RZ Yu, AA Levin
Current Opinion in Investigational Drugs 2001, 2:562-571 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Genasense (Genta Inc)
D Banerjee
Current Opinion in Investigational Drugs 2001, 2:574-580 (6April2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
D Witty, Gasparo M de, M Williams, C Darlington, E Boven, G Damia, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:581 (17May2001)
[Abstract] [Full text] [PDF]


Patent selection
H Mucke
Current Opinion in Investigational Drugs 2001, 2:592 (17May2001)
[Abstract] [Full text] [PDF]


Patent alert
OA Phillips, IB Duncan, WM Brown, HAM Muckle, P Norman
Current Opinion in Investigational Drugs 2001, 2:595 (17May2001)
[Abstract] [Full text] [PDF]


Prevention of viral drug resistance by novel combination therapy.
WF Mangel, MT Brown, ML Baniecki, D Barnard, WJ McGrath
Current Opinion in Investigational Drugs 2001, 2:613 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Entecavir (Bristol-Myers Squibb).
A Billich
Current Opinion in Investigational Drugs 2001, 2:617 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Genvir (Flamel Technologies).
DL Barnard
Current Opinion in Investigational Drugs 2001, 2:622 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Shifting attention from one cell type to another in dermatological research, but where are the new drugs?
C Korstanje
Current Opinion in Investigational Drugs 2001, 2:624 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Retinoids for the treatment of psoriasis: Outlook for the future
S Kuenzil, J-H Saurat
Current Opinion in Investigational Drugs 2001, 2:625 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Alefacept (Biogen).
SJ Bashir, HI Maibach
Current Opinion in Investigational Drugs 2001, 2:631 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


IDEC-114 (IDEC)
RE Schopf
Current Opinion in Investigational Drugs 2001, 2:635 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cell therapy approaches for the treatment of diabetes.
S Efrat
Current Opinion in Investigational Drugs 2001, 2:639 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Treatment of gynecomastia.
U Gruntmanis, GD Braunstein
Current Opinion in Investigational Drugs 2001, 2:643 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


CLX-0901 (Calyx Therapeutics)
D Barlocco
Current Opinion in Investigational Drugs 2001, 2:650 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Therapeutic strategies to retard neuronal cell death in neurodegenerative diseases.
RE Davis
Current Opinion in Investigational Drugs 2001, 2:654 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pathogenesis of Parkinson's disease.
TB Sherer, R Betarbet, T Greenamyre
Current Opinion in Investigational Drugs 2001, 2:657 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


AN-1792 (Elan).
U Thattle
Current Opinion in Investigational Drugs 2001, 2:663 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


KW-6002 (Kyowa Hakko Kogyo).
LJS Knutsen
Current Opinion in Investigational Drugs 2001, 2:668 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Developing novel and highly effective new therapeutic strategies for treatment of colorectal cancer: Where do we go from here?
JA Houghton
Current Opinion in Investigational Drugs 2001, 2:674 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Sulindac and its derivatives: A novel class of anticancer agents.
C Haanen
Current Opinion in Investigational Drugs 2001, 2:677 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Apoptosis modulators as cancer therapeutics.
LZ Penn
Current Opinion in Investigational Drugs 2001, 2:684 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Thymitaq (Zarix).
I Niculescu-Duvaz
Current Opinion in Investigational Drugs 2001, 2:693 (17May2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
T Jones, M Daneshtalab, S Doggrell, F Barone, M Williams, B Leonard, A Palmer, C Darlington, P Smith, E Boven, D Giovanna, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:707-724 (20June2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:725-729 (20June2001)
[Abstract] [Full text] [PDF]


Patent alert
WM Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:730-741 (20June2001)
[Abstract] [Full text] [PDF]


Overview: Perspectives on genomics and antibiotic discovery.
J Trias
Current Opinion in Investigational Drugs 2001, 2:742-744 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Antibacterial agents (oxazolidinones, quinolones, macrolides and new agents): Patent highlights June to December 2000.
OA Phillips, WC Matowe
Current Opinion in Investigational Drugs 2001, 2:745-751 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


RU-79115 (Aventis Pharma).
SC Annedi, LP Kotra
Current Opinion in Investigational Drugs 2001, 2:752-754 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Tobramycin (Cystic Fibrosis Foundation/PathoGenesis).
MP Singh
Current Opinion in Investigational Drugs 2001, 2:755-765 (9November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ABT-773 (Abbott).
LE Lawrence
Current Opinion in Investigational Drugs 2001, 2:766-772 (20June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ABT-773 Abbott Laboratories
LE Lawrence
Current Opinion in Investigational Drugs 2001, 2:766 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The CD40-CD40 ligand system: A potential therapeutic target in atherosclerosis.
RP Phipps, L Koumas, E Leung, SY Reddy, T Blieden, J Kaufman
Current Opinion in Investigational Drugs 2001, 2:773-777 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Macrophage migration inhibitory factor as a target molecule in multiple sclerosis.
J Nishihira, A Ogata
Current Opinion in Investigational Drugs 2001, 2:778-782 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


New developments in the treatment of ischemia/reperfusion injury.
Robichaud A Fox, HK Ondiveeran
Current Opinion in Investigational Drugs 2001, 2:783-791 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


AdGVVEGF121.10 (GenVec).
N Basara
Current Opinion in Investigational Drugs 2001, 2:792-795 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


VEGF-2 (St Elizabeth's Medical Center).
PKF Yeung
Current Opinion in Investigational Drugs 2001, 2:796-800 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Acute spinal cord injury: Pharmacotherapy and drug development perspectives.
AR Blight, MP Zimber
Current Opinion in Investigational Drugs 2001, 2:801-808 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Safinamide (Newron Pharmaceuticals).
PL Chazot
Current Opinion in Investigational Drugs 2001, 2:809-813 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Gacyclidine (Beaufour-Ipsen).
APA Mitha, KI Maynard
Current Opinion in Investigational Drugs 2001, 2:814-819 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMS-204352 (Bristol-Myers Squibb).
KB Mackay
Current Opinion in Investigational Drugs 2001, 2:820-823 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Soretolide (Laboratoires Biocodex).
MO Fatope
Current Opinion in Investigational Drugs 2001, 2:824-827 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pregabalin (Pfizer).
I Selak
Current Opinion in Investigational Drugs 2001, 2:828-834 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Gene-directed enzyme prodrug therapy (GDEPT) - recognizing the present limitations of gene therapy for the treatment of cancer.
RJ Knox
Current Opinion in Investigational Drugs 2001, 2:835-838 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Use of hypoxia-regulated gene expression in tumor-specific gene therapy.
DF Deen, H Ruan
Current Opinion in Investigational Drugs 2001, 2:839-843 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


GVAX (Cell Genesys).
R Dummer
Current Opinion in Investigational Drugs 2001, 2:844-848 (18June2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, D Witty, S Doggrell, D Lane, M Williams, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:849-863 (11July2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:864-867 (11July2001)
[Abstract] [Full text] [PDF]


Patent alert
IB Duncan, WM Brown, P Norman, HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:868-889 (11July2001)
[Abstract] [Full text] [PDF]


PIV-3 Vaccine (National Institutes of Health/Aviron).
T Jones
Current Opinion in Investigational Drugs 2001, 2:890-892 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Rotavirus vaccine (AVANT/GlaxoSmithKline).
T Jones
Current Opinion in Investigational Drugs 2001, 2:893-895 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Helivax (Antex Biologics).
GD Giudice
Current Opinion in Investigational Drugs 2001, 2:896-899 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Anti-inflammatory approaches to the treatment of cystic fibrosis lung disease: Past, present and future
CM Oermann
Current Opinion in Investigational Drugs 2001, 2:900-906 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Targeting selectins for the treatment of respiratory diseases
SJ Romano, DH Slee
Current Opinion in Investigational Drugs 2001, 2:907-913 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


CpG oligodeoxynucleotides in asthma
I Hussain, JN Kline
Current Opinion in Investigational Drugs 2001, 2:914-918 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Nepadutant (Menarini Richerche).
A Ahluwalia
Current Opinion in Investigational Drugs 2001, 2:919-922 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


New pharmacological strategies for the treatment of heart failure
BSP Chin, GYH Lip
Current Opinion in Investigational Drugs 2001, 2:923-928 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BNP in decompensated heart failure: Diagnostic, prognostic and therapeutic potential
MR Burger, AJ Burger
Current Opinion in Investigational Drugs 2001, 2:929-935 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


JTV-519 (Japan Tobacco).
HF Tse, WF Lam
Current Opinion in Investigational Drugs 2001, 2:936-939 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Use of atypical antipsychotics in mood disorders
R Weizman, A Weizman
Current Opinion in Investigational Drugs 2001, 2:940-945 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


SB-277011 (GlaxoSmithKline).
G Remington, S Kapur
Current Opinion in Investigational Drugs 2001, 2:946-949 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Osanetant (Sanofi-Synthelabo).
F Kamali
Current Opinion in Investigational Drugs 2001, 2:950-956 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Immunotherapy for cancer: Focusing on developing treatments rather than drugs
M Sznol
Current Opinion in Investigational Drugs 2001, 2:957-958 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Immunization against tumor cell surface complement-regulatory proteins
LG Durrant, I Spendlove
Current Opinion in Investigational Drugs 2001, 2:959-966 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Small-molecule cytokine inducers causing tumor necrosis
BC Baguley
Current Opinion in Investigational Drugs 2001, 2:967-975 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Leuvectin (Vical Inc).
A Kaushik
Current Opinion in Investigational Drugs 2001, 2:976-981 (11July2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, M Elices, S Doggrell, M Gasparo, M Williams, C Darlington, P Smith, E Boven, G Damia, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:983-1002 (8August2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1003-1006 (8August2001)
[Abstract] [Full text] [PDF]


Patent alert
OA Phillips, P Norman, WM Brown, HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1007-1027 (8August2001)
[Abstract] [Full text] [PDF]


Delivering novel targets and antibiotics from genomics.
D Payne, DJ Holmes, M Rosenberg
Current Opinion in Investigational Drugs 2001, 2:1028-1034 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


THF carbapenems (Wyeth Ayerst).
N Jiraskova
Current Opinion in Investigational Drugs 2001, 2:1035-1038 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Oritavancin (Eli Lilly & Co).
JF Barrett
Current Opinion in Investigational Drugs 2001, 2:1039-1044 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Novel therapies in the treatment of systemic lupus erythematosus.
CR Dequet, DJ Wallace
Current Opinion in Investigational Drugs 2001, 2:1045-1053 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Angiogenesis: A therapeutic target in arthritis.
DA Walsh, L Haywood
Current Opinion in Investigational Drugs 2001, 2:1054-1063 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Arthritic diseases: Melanocortin type 3 receptor agonists as potential therapeutics.
SJ Getting, M Perretti
Current Opinion in Investigational Drugs 2001, 2:1064-1069 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


VX-745 (Vertex Pharmaceuticals).
JJ Haddad
Current Opinion in Investigational Drugs 2001, 2:1070-1076 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Overview: From heparin to low molecular weight heparin: Beyond anticoagulation.
SA Mousa, J Fareed
Current Opinion in Investigational Drugs 2001, 2:1077-1080 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The potential of erythropoietin and related strategies to stimulate erythropoiesis.
KU Eckardt
Current Opinion in Investigational Drugs 2001, 2:1081-1085 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Antiplatelet therapies: Platelet GPIIb/IIIa antagonists and beyond.
K Konstantopoulos, SA Mousa
Current Opinion in Investigational Drugs 2001, 2:1086-1092 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


YM-337 (Yamanouchi).
S Kamath, GYH Lip
Current Opinion in Investigational Drugs 2001, 2:1093-1096 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Darbepoetin alfa (Amgen).
F Locatelli, L Vecchio
Current Opinion in Investigational Drugs 2001, 2:1097-1104 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Pharmacogenomics of psychiatric disorders - Separating the dreams from the realities.
M Briley, C Moret
Current Opinion in Investigational Drugs 2001, 2:1105-1107 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Rodent models of anxiety-like behaviors: Are they predictive for compounds acting via non-benzodiazepine mechanisms?
C Belzung
Current Opinion in Investigational Drugs 2001, 2:1108-1111 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Glutamate receptor ligands as anxiolytics.
Wojcik E Chojnacka, A Klodzinska, A Pilc
Current Opinion in Investigational Drugs 2001, 2:1112-1119 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Gepirone (Organon).
RA Leslie
Current Opinion in Investigational Drugs 2001, 2:1120-1127 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Changing times: Developing cancer drugs in genomeland.
P Workman
Current Opinion in Investigational Drugs 2001, 2:1128-1135 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Mutant p53: The loaded gun.
G Selivanova
Current Opinion in Investigational Drugs 2001, 2:1136-1141 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


SU-6668 (SUGEN).
D Fabbro, PW Manley
Current Opinion in Investigational Drugs 2001, 2:1142-1148 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Flavopiridol (National Cancer Institute).
HK Wang
Current Opinion in Investigational Drugs 2001, 2:1149-1155 (8August2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, T Jones, M Williams, C Darlington, P Smith, S Doggrell, L Hofseth, RE Hurst
Current Opinion in Investigational Drugs 2001, 2:1157-1171 (3September2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1172-1175 (3September2001)
[Abstract] [Full text] [PDF]


Patent alert
WM Brown, HAM Mucke, P Norman
Current Opinion in Investigational Drugs 2001, 2:1176-1190 (3September2001)
[Abstract] [Full text] [PDF]


Immunotherapy as an adjunct to highly-active antiretroviral therapy.
Corb M Murphey, Fuller D Heydenburg
Current Opinion in Investigational Drugs 2001, 2:1191-1197 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Peptide-lead CXCR4 antagonists with high anti-HIV activity.
N Fujii, H Tamamura
Current Opinion in Investigational Drugs 2001, 2:1198-1202 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


AIDSVAX (VaxGen)
A Billich
Current Opinion in Investigational Drugs 2001, 2:1203-1208 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


DPC-083 (DuPont Pharmaceuticals)
ML Lim
Current Opinion in Investigational Drugs 2001, 2:1209-1212 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Lck inhibitors as a therapeutic approach to autoimmune disease and transplant rejection.
JS Kamens, SE Ratnofsky, GC Hirst
Current Opinion in Investigational Drugs 2001, 2:1213-1219 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Everolimus (Novartis)
FJ Dumont
Current Opinion in Investigational Drugs 2001, 2:1220-1234 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: 3rd Report of the National Cholesterol Education Program (NCEP III): A switch from dietary modification to risk factor assessment
DM Lane
Current Opinion in Investigational Drugs 2001, 2:1235-1236 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Restenosis drug discovery - a formidable task.
CQ Meng
Current Opinion in Investigational Drugs 2001, 2:1237-1246 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


VasoCare (Vasogen)
F Visioli
Current Opinion in Investigational Drugs 2001, 2:1247-1248 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Mutant P/Q-type calcium channel electrophysiology and migraine.
JJ Plomp, AMJM van den Maagdenberg, PC Molenaar, RR Frants, MD Ferrari
Current Opinion in Investigational Drugs 2001, 2:1250-1260 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Development of CGRP antagonists for the treatment of migraine.
H Doods
Current Opinion in Investigational Drugs 2001, 2:1261-1268 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cizolirtine (Laboratorios Dr Esteve).
N Monck
Current Opinion in Investigational Drugs 2001, 2:1269-1272 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


LY-293558 (Eli Lilly & Co).
I Gilron
Current Opinion in Investigational Drugs 2001, 2:1273-1278 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: STI-571: Current status and future prospects.
CA Schiffer
Current Opinion in Investigational Drugs 2001, 2:1279-1281 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Chimeric fusion proteins - Pseudomonas exotoxin-based.
RJ Kreitman
Current Opinion in Investigational Drugs 2001, 2:1282-1293 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Chimeric fusion proteins - diphtheria toxin-based.
AE Frankel, BL Powell, DA Vallera, DM Neville
Current Opinion in Investigational Drugs 2001, 2:1294-1301 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Thalidomide: An old sedative-hypnotic with anticancer activity?
G Gasparini, A Morabito, E Magnani, D Gattuso, B Capaccetti, AM Alberti
Current Opinion in Investigational Drugs 2001, 2:1302-1308 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


hIL-13-PE38QQR (NeoPharm)
S Barth
Current Opinion in Investigational Drugs 2001, 2:1309-1313 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


SGN-10 (Seattle Genetics)
SV Smith
Current Opinion in Investigational Drugs 2001, 2:1314-1319 (3September2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, T Jones, S Doggrell, Gasparo M de, M Williams, RE Hurst, E Boven
Current Opinion in Investigational Drugs 2001, 2:1321-1333 (9October2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1334-1336 (9October2001)
[Abstract] [Full text] [PDF]


Patent alert
IB Duncan, WM Brown, P Norman, HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1337-1363 (9October2001)
[Abstract] [Full text] [PDF]


Overview: Antifungal combination therapy.
AM Sugar
Current Opinion in Investigational Drugs 2001, 2:1364-1365 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Non-fumigatus species of Aspergillus: Perspectives on emerging pathogens in immunocompromised hosts.
TJ Walsh, AH Groll
Current Opinion in Investigational Drugs 2001, 2:1366-1367 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Anti-toxoplasmosis drugs.
F Derouin
Current Opinion in Investigational Drugs 2001, 2:1368-1374 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The treatment of pulmonary aspergilloma.
MA Judson, DA Stevens
Current Opinion in Investigational Drugs 2001, 2:1375-1377 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Nod2, cause of, or contributor to, Crohn's disease.
NA Punchard
Current Opinion in Investigational Drugs 2001, 2:1378-1381 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The role of the gut lymphoid tissue in induction of oral tolerance.
F Song, CC Whitacre
Current Opinion in Investigational Drugs 2001, 2:1382-1386 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Anti-inflammatory peptides and proteins in inflammatory bowel disease.
M Veljaca
Current Opinion in Investigational Drugs 2001, 2:1387-1394 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Oprelvekin (Genetics Institute).
SV Sitaraman, AT Gerwirtz
Current Opinion in Investigational Drugs 2001, 2:1395-1400 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Alicaforsen (Isis Pharmaceuticals).
AT Gerwirtz, S Sitaraman
Current Opinion in Investigational Drugs 2001, 2:1401-1406 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pharmacological treatment of portal hypertension.
J Gonzalez-Abraldes, J Bosch, JC Garcia-Pagan
Current Opinion in Investigational Drugs 2001, 2:1407-1413 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Omapatrilat (Bristol-Myers Squibb).
R Tabrizchi
Current Opinion in Investigational Drugs 2001, 2:1414-1422 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


SR-121463 (Sanofi-Synthelabo).
A Martinez-Castelao
Current Opinion in Investigational Drugs 2001, 2:1423-1427 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: H3 histamine receptor isoforms: New therapeutic targets in the CNS?
PL Chazot, V Hann
Current Opinion in Investigational Drugs 2001, 2:1428-1431 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cilansetron (Solvay).
G Stacher
Current Opinion in Investigational Drugs 2001, 2:1432-1436 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


TAK-637 (Takeda).
JB Furness
Current Opinion in Investigational Drugs 2001, 2:1437-1440 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Ezlopitant (Pfizer Inc)
S Evangelista
Current Opinion in Investigational Drugs 2001, 2:1441-1443 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Drug properties of second generation antisense oligonucleotides: How do they measure up to their predecessors?
SP Henry, RS Geary, R Yu, AA Levin
Current Opinion in Investigational Drugs 2001, 2:1444-1449 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cellular uptake of antisense oligonucleotides.
AM Tari, G Lopez-Berestein
Current Opinion in Investigational Drugs 2001, 2:1450-1453 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ISIS-3521 (Isis Pharmaceuticals)
K Li, J Zhang
Current Opinion in Investigational Drugs 2001, 2:1454-1461 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


GTI-2040 (Lorus Therapeutics)
RM Orr
Current Opinion in Investigational Drugs 2001, 2:1462-1466 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


GTI-2501 (Lorus Therapeutics)
G-c Tu, X Tu
Current Opinion in Investigational Drugs 2001, 2:1467 (9October2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtaab, S Doggrell, F Barone, RE Hurst, G Damia
Current Opinion in Investigational Drugs 2001, 2:1471-1482 (12November2001)
[Abstract] [Full text] [PDF]


Patent selection
H Mucke
Current Opinion in Investigational Drugs 2001, 2:1483-1485 (12November2001)
[Abstract] [Full text] [PDF]


Patent alert
IB Duncan, WM Brown, P Norma, H Mucke
Current Opinion in Investigational Drugs 2001, 2:1486-1515 (12November2001)
[Abstract] [Full text] [PDF]


Hepatitis C virus: Prospects for future therapies
TC Wilikinson
Current Opinion in Investigational Drugs 2001, 2:1516-1522 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ISIS-14803 (Isis Pharmaceuticals)
GW Witherell
Current Opinion in Investigational Drugs 2001, 2:1523-1529 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pegasys (Hoffmann-La Roche)
DL Barnard
Current Opinion in Investigational Drugs 2001, 2:1530-1538 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Biological activity of tyrosine kinase inhibitors: Novel agents for psoriasis therapy
Bassat H Ben
Current Opinion in Investigational Drugs 2001, 2:1539-1545 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Targeting interleukin-2 as a treatment for psoriasis
A Salim, R Emerson
Current Opinion in Investigational Drugs 2001, 2:1546-1548 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Targeting phospholipase A2 for the treatment of inflammatory skin diseases
JR Burke
Current Opinion in Investigational Drugs 2001, 2:1549-1552 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Immunotherapeutic approaches for the treatment of malignant melanoma
Lewandrowski C Curiel, MB Atkins
Current Opinion in Investigational Drugs 2001, 2:1553-1563 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Mechanism of action of thiazolidinediones.
M Flemmer, J Scott
Current Opinion in Investigational Drugs 2001, 2:1564-1567 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Current and future treatment strategies for type 2 diabetes: The beta-cell as a therapeutic target.
B Tyrberg, F Levine
Current Opinion in Investigational Drugs 2001, 2:1568-1574 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Pramlintide (Amylin)
D Barlocco
Current Opinion in Investigational Drugs 2001, 2:1575-1581 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Parkinson's disease and D(1) dopamine receptors
R Mailman, X Huang, DE Nichols
Current Opinion in Investigational Drugs 2001, 2:1582-1591 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


NS-2330 (NeuroSearch)
U Thatte
Current Opinion in Investigational Drugs 2001, 2:1592-1594 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


TAK-147 (Takeda)
H Mucke
Current Opinion in Investigational Drugs 2001, 2:1595-1599 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview - Rational integration of agents directed at novel therapeutic targets into combination chemotherapeutic regimens
S Grant, P Dent
Current Opinion in Investigational Drugs 2001, 2:1600-1605 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


The Hsp90 chaperone as a promising drug target.
PW Piper
Current Opinion in Investigational Drugs 2001, 2:1606-1610 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Pemetrexed disodium (Eli Lilly)
P Norman
Current Opinion in Investigational Drugs 2001, 2:1611-1622 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Alanosine (UCSD)
J Yu
Current Opinion in Investigational Drugs 2001, 2:1623-1630 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ET-743 (PharmaMar/NCI/Ortho Biotech)
CF Verschraegen, K Glover
Current Opinion in Investigational Drugs 2001, 2:1631 (12November2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Paper alert
M Daneshtalab, S Doggrell, F Barone, RE Hurst, G Damia
Current Opinion in Investigational Drugs 2001, 2:1639-1653 (20December2001)
[Abstract] [Full text] [PDF]


Patent selection
HAM Mucke
Current Opinion in Investigational Drugs 2001, 2:1654-1657 (20December2001)
[Abstract] [Full text] [PDF]


Patent alert
IB Duncan, WM Brown, P Norman, H Mucke
Current Opinion in Investigational Drugs 2001, 2:1658-1680 (20December2001)
[Abstract] [Full text] [PDF]


Combinatorial biosynthesis in microorganisms as a route to new antimicrobial, antitumor and neuroregenerative drugs.
CR Hutchinson, R McDaniel
Current Opinion in Investigational Drugs 2001, 2:1681-1690 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Telithromycin (Aventis Pharma).
AP Johnson
Current Opinion in Investigational Drugs 2001, 2:1691-1701 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


HMR-3562 (Aventis Pharma).
Z Ma, AS Florjancic
Current Opinion in Investigational Drugs 2001, 2:1702-1705 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


T-3811 (Toyama/Bristol-Myers Squibb).
R Frechette
Current Opinion in Investigational Drugs 2001, 2:1706-1711 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Targeting the chemokine system for multiple sclerosis treatment.
AR Glabinski, RM Ransohoff
Current Opinion in Investigational Drugs 2001, 2:1712-1719 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


Endothelium as a pharmacological target.
P d'Alessio
Current Opinion in Investigational Drugs 2001, 2:1720-1724 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Etanercept (Immunex).
MK Pugsley
Current Opinion in Investigational Drugs 2001, 2:1725-1731 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


An update of neuroprotectants in clinical development for acute stroke.
H Lutsep, W Clark
Current Opinion in Investigational Drugs 2001, 2:1732-1736 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


UK-315716/UK-240455 (Pfizer).
AM Capelli, F Micheli
Current Opinion in Investigational Drugs 2001, 2:1737-1739 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


KB-R7943 (Kanebo).
GE Billman
Current Opinion in Investigational Drugs 2001, 2:1740-1745 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: A molcule for all occasions.
T Alexi
Current Opinion in Investigational Drugs 2001, 2:1740-1745 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Pro-inflammatory cytokines in cerebrovascular ischemia.
K Kumar
Current Opinion in Investigational Drugs 2001, 2:1748-1750 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Cladribine (Ortho Biotech Inc).
C Tortorella, M Rovaris, M Filippi
Current Opinion in Investigational Drugs 2001, 2:1751-1756 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Citicoline (Ferrer Internacional).
AV Alexandrov
Current Opinion in Investigational Drugs 2001, 2:1757-1762 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Losigamone (Dr Wilmar Schwabe).
LJ Willmore
Current Opinion in Investigational Drugs 2001, 2:1763-1766 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


Overview: Synthetic gene delivery: Another quest for the Holy Grail?
A Rolland
Current Opinion in Investigational Drugs 2001, 2:1767-1769 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


ONYX-015 (Onyx Pharmaceuticals).
EEW Cohen, CM Rudin
Current Opinion in Investigational Drugs 2001, 2:1770-1775 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]


INGN-201 (Introgen Therapeutics).
I Brukner
Current Opinion in Investigational Drugs 2001, 2:1776 (20December2001)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

 

 

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