| | Current Opinion in Investigational Drugs, Volume 10 |
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Paper alert
M Daneshtalab, SA Antoniu, MJ Elices, K-S Oh, S Lee, KY Yi, HW Seo, HN Koo, BH Lee, S Doggrell, M Williams, N Levens, R Hurst
Current Opinion in Investigational Drugs 2009, 10:1-8 (23 December2008)
[Abstract] [Full text] [PDF]
Patent alert
C Whelan, HAM Mucke, C Yeates, P Norman
Current Opinion in Investigational Drugs 2009, 10:9-19 (23December2008)
[Abstract] [Full text] [PDF]
Is urological research stalled or stopped?
MG Wyllie
Current Opinion in Investigational Drugs 2009, 10:20-22 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Progress in Alzheimer's disease drug discovery: An update
M Williams
Current Opinion in Investigational Drugs 2009, 10:23-34 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Pharmacotherapy in post-traumatic stress disorder: Evidence from
randomized controlled trials
GM Sullivan, Y Neria
Current Opinion in Investigational Drugs 2009, 10:35-45 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Endothelial dysfunction: A potential therapeutic target for geriatric
depression and brain amyloid deposition in Alzheimer's disease?
E Isingrini, T Desmidt, C Belzung, V Camus
Current Opinion in Investigational Drugs 2009, 10:46-55 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The manipulation of cation-chloride co-transporters as a novel means
to treat persistent pain, epilepsy and other neurological disorders
JAM Coull, M Gagnon
Current Opinion in Investigational Drugs 2009, 10:56-61 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The pharmacological mechanisms of electroacupuncture
Y Fukazawa, T Maeda, S Kishioka
Current Opinion in Investigational Drugs 2009, 10:62-69 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The relationship between dysglycemia and cognitive dysfunction
T Cukierman-Yaffee
Current Opinion in Investigational Drugs 2009, 10:70-74 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Desvenlafaxine, a serotonin-norepinephrine uptake inhibitor for major
depressive disorder, neuropathic pain and the vasomotor symptoms
associated with menopause
CU Pae, MH Park, DM Marks, C Han, AA Patkar, PS Masand
Current Opinion in Investigational Drugs 2009, 10:75-90 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Gabapentin enacarbil, a gabapentin prodrug for the treatment of the
neurological symptoms associated with disorders such as restless legs
syndrome
G Merlino, A Serafini, JJ Young, F Robiony, GL Gigli, M Valente
Current Opinion in Investigational Drugs 2009, 10:91-102 (23December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens
Current Opinion in Investigational Drugs 2009, 10:103-108 (3February2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2009, 10:109-118 (3February2009)
[Abstract] [Full text] [PDF]
Old drugs resurrected?
JD Thomas, JG Moloughney, JH Toney
Current Opinion in Investigational Drugs 2009, 10:119-120 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Ribosomal frameshifting: An emerging drug target for HIV
PC Gareiss, BL Miller
Current Opinion in Investigational Drugs 2009, 10:121-128 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
New approaches for inhibiting HIV integrase: A journey beyond the active site
MA Walker
Current Opinion in Investigational Drugs 2009, 10:129-136 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Current developments in anti-HIV/AIDS gene therapy
AY Tsygankov
Current Opinion in Investigational Drugs 2009, 10:137-149 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Treatment of multiresistant Acinetobacter baumannii infections
J Pach  n, J Vila
Current Opinion in Investigational Drugs 2009, 10:150-156 (3February2009)
[Abstract] [Full text] [PDF]
Challenges in developing new antibacterial drugs
KJ Williams, RP Bax
Current Opinion in Investigational Drugs 2009, 10:157-163 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Host defense peptides for use as potential therapeutics
L Zhang, TJ Falla
Current Opinion in Investigational Drugs 2009, 10:164-171 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Addressing the challenge of extended-spectrum beta-lactamases
J-R Zahar, O Lortholary, C Martin, G Potel, P Plesiat, P Nordmann
Current Opinion in Investigational Drugs 2009, 10:172-180 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection
I Mederacke, H Wedemeyer, MP Manns
Current Opinion in Investigational Drugs 2009, 10:181-189 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Elvitegravir, an oral HIV integrase inhibitor, for the potential treatment of HIV infection
OM Klibanov
Current Opinion in Investigational Drugs 2009, 10:190-200 (3February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2009, 10:201-208 (2March2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2009, 10:209-216 (2March2009)
[Abstract] [Full text] [PDF]
Drug development research: Diabetes favored over cardiovascular disease?
K Suckling
Current Opinion in Investigational Drugs 2009, 10:217-219 (2March2009)
[Abstract] [Full text] [PDF]
Ischemic stroke intervention requires mixed cellular protection of
the penumbra
FC Barone
Current Opinion in Investigational Drugs 2009, 10:220-223 (2March2009)
[Abstract] [Full text] [PDF]
The use of lipid-lowering drug therapy in children and adolescents
HJ Avis, MN Vissers, FA Wijburg, JJP Kastelein, BA Hutten
Current Opinion in Investigational Drugs 2009, 10:224-231 (2March2009)
[Abstract] [Full text] [PDF]
The role of a murine transplantation model of atherosclerosis regression in drug discovery
JE Feig, JS Quick, EA Fisher
Current Opinion in Investigational Drugs 2009, 10:232-238 (2March2009)
[Abstract] [Full text] [PDF]
Reassessing the validity of surrogate markers of drug efficacy in the treatment of coronary artery disease
TJ Colatsky
Current Opinion in Investigational Drugs 2009, 10:239-244 (2March2009)
[Abstract] [Full text] [PDF]
'Muscle-sparing' statins: Preclinical profiles and future clinical use
JA Pfefferkorn
Current Opinion in Investigational Drugs 2009, 10:245-252 (2March2009)
[Abstract] [Full text] [PDF]
Soluble epoxide hydrolase: A new target for cardioprotection
GJ Gross, K Nithipatikom
Current Opinion in Investigational Drugs 2009, 10:253-258 (2March2009)
[Abstract] [Full text] [PDF]
NV1FGF, a pCOR plasmid-based angiogenic gene therapy for the treatment of intermittent claudication and critical limb ischemia
N Maulik
Current Opinion in Investigational Drugs 2009, 10:259-268 (2March2009)
[Abstract] [Full text] [PDF]
CYT-006-AngQb, a vaccine against angiotensin II for the potential treatment of hypertension
S Phisitkul
Current Opinion in Investigational Drugs 2009, 10:269-275 (2March2009)
[Abstract] [Full text] [PDF]
LA-419, a nitric-oxide donor for the treatment of cardiovascular disorders
IL Megson, SJ Leslie
Current Opinion in Investigational Drugs 2009, 10:276-285 (2March2009)
[Abstract] [Full text] [PDF]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2009, 10:287-293 (30March2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2009, 10:294-302 (30March2009)
[Abstract] [Full text] [PDF]
The drugs from within
FF Jr Bolander
Current Opinion in Investigational Drugs 2009, 10:303-304 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Endocannabinoids and reproductive endocrinology
M Maccarrone
Current Opinion in Investigational Drugs 2009, 10:305-310 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Kisspeptin offers a novel therapeutic target in reproduction
CN Jayasena, WS Dhillo
Current Opinion in Investigational Drugs 2009, 10:311-318 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Aldosterone synthase inhibitors: Pharmacological and clinical aspects
PM Jansen, den Meiracker AH van, AHJ Danser
Current Opinion in Investigational Drugs 2009, 10:319-326 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Treating diabetic retinopathy by inhibiting growth factor pathways
RN Frank
Current Opinion in Investigational Drugs 2009, 10:327-335 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Engineered antibodies for type 1 diabetes
CS Hampe
Current Opinion in Investigational Drugs 2009, 10:336-345 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The adipocyte IKK/NFkappaB pathway: A therapeutic target
for insulin resistance
H Ruan, HJ Pownall
Current Opinion in Investigational Drugs 2009, 10:346-352 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
4-Hydroxyisoleucine: A plant-derived treatment for metabolic syndrome
L Jett , L Harvey, K Eugeni, N Levens
Current Opinion in Investigational Drugs 2009, 10:353-358 (30March2009)
[Abstract] [Full text] [PDF]
FGF21: A novel prospect for the treatment of metabolic diseases
A Kharitonenkov, AB Shanafelt
Current Opinion in Investigational Drugs 2009, 10:359-364 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
MF-101, an estrogen receptor beta agonist for the treatment of vasomotor symptoms in peri- and postmenopausal women
DW Stovall, JV Pinkerton
Current Opinion in Investigational Drugs 2009, 10:365-371 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Corifollitropin alfa, a long-acting follicle-stimulating hormone agonist for the treatment of infertility
D Loutradis, P Drakakis, A Vlismas, A Antsaklis
Current Opinion in Investigational Drugs 2009, 10:372-380 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
INT-131, a PPARgamma agonist for the treatment of type 2 diabetes
U Kintscher, M Goebel
Current Opinion in Investigational Drugs 2009, 10:381-387 (30March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2009, 10:389-395 (5May2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2009, 10:396-403 (5May2009)
[Abstract] [Full text] [PDF]
Challenges in targeting TNFalpha in asthma and COPD
SA Antoniu
Current Opinion in Investigational Drugs 2009, 10:404-406 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Pharmacotherapy for multiple sclerosis: Progress and prospects
AM Palmer
Current Opinion in Investigational Drugs 2009, 10:407-417 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
siRNA for inflammatory diseases
BC Ponnappa
Current Opinion in Investigational Drugs 2009, 10:418-424 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Angiogenesis inhibitors for the treatment of chronic autoimmune inflammatory arthritis
N Schoettler, E Brahn
Current Opinion in Investigational Drugs 2009, 10:425-433 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Age-related macular degeneration: An immunologically driven disease
RB Nussenblatt, B iu, Z Li
Current Opinion in Investigational Drugs 2009, 10:434-442 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Recent developments in IBD and the B7 family of costimulatory molecules
HA Arnett, JL Viney
Current Opinion in Investigational Drugs 2009, 10:443-451 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The IL-12/IL-23 axis and its role in Th17 cell development, pathology and plasticity in arthritis
F Cornelissen, Hamburg JP van, E Lubberts
Current Opinion in Investigational Drugs 2009, 10:452-462 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Autoimmunity in autism
AM Enstrom, de Water JA van, P Ashwood
Current Opinion in Investigational Drugs 2009, 10:463-473 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Aczone, a topical gel formulation of the antibacterial,
anti-inflammatory dapsone for the treatment of acne
N Scheinfeld
Current Opinion in Investigational Drugs 2009, 10:474-481 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Aclidinium bromide, a novel long-acting muscarinic M3 antagonist for the treatment of COPD
M Cazzola
Current Opinion in Investigational Drugs 2009, 10:482-490 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
CP-690550, a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders
K West
Current Opinion in Investigational Drugs 2009, 10:491-504 (5May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Erratum [Frank R: Treating diabetic retinopathy by inhibiting growth factor pathways COID (2009) 10(4):327-335. Correction to figure legend on page 328]
Current Opinion in Investigational Drugs 2009, 10:505 (7May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2009, 10:507-514 (5June2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Whelan, C Yeates
Current Opinion in Investigational Drugs 2009, 10:515-522 (5June2009)
[Abstract] [Full text] [PDF]
Mitochondrial function as an emerging 'target of interest' for
cancer treatment
EA Sausville
Current Opinion in Investigational Drugs 2009, 10:523-525 (5June2009)
[Abstract] [Full text] [PDF]
Dendritic cells in immunotherapy of established cancer: Roles of signals 1, 2, 3 and 4
P Kalinski
Current Opinion in Investigational Drugs 2009, 10:526-535 (5June2009)
[Abstract] [Full text] [PDF]
The mechanism of action of plitidepsin
MJ Mu oz-Alonso, L Gonz lez-Santiago, T Mart-nez, A Losada, CM Galmarini, A Muoz
Current Opinion in Investigational Drugs 2009, 10:536-542 (5June2009)
[Abstract] [Full text] [PDF]
The IL-17/IL-23 axis of inflammation in cancer: Friend or foe?
N Martin-Orozco, C Dong
Current Opinion in Investigational Drugs 2009, 10:543-549 (5June2009)
[Abstract] [Full text] [PDF]
Hyperthermia as an immunotherapy strategy for cancer
JJ Skitzki, EA Repasky, SS Evans
Current Opinion in Investigational Drugs 2009, 10:550-558 (5June2009)
[Abstract] [Full text] [PDF]
The development and testing of aptamers for cancer
AS Barbas, RR White
Current Opinion in Investigational Drugs 2009, 10:572-578 (5June2009)
[Abstract] [Full text] [PDF]
Dacetuzumab, a humanized mAb against CD40 for the treatment of hematological malignancies
S Khubchandani, MS Czuczman, FJ Hernandez-Ilizaliturri
Current Opinion in Investigational Drugs 2009, 10:579-587 (5June2009)
[Abstract] [Full text] [PDF]
GA-101, a third-generation, humanized and glyco-engineered anti-CD20 mAb for the treatment of B-cell lymphoid malignancies
T Robak
Current Opinion in Investigational Drugs 2009, 10:588-596 (5June2009)
[Abstract] [Full text] [PDF]
Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer
Y Krupitskaya, HA Wakelee
Current Opinion in Investigational Drugs 2009, 10:597-605 (5June2009)
[Abstract] [Full text] [PDF]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2009, 10:607-612 (30June2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:613-621 (30June2009)
[Abstract] [Full text] [PDF]
Let's get some structure into neuroscience drug discovery
S England
Current Opinion in Investigational Drugs 2009, 10:622-623 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Vascular cognitive impairment: Dementia biology and translational animal models
FC Barone, DM Rosenbaum, J Zhou, H Crystal
Current Opinion in Investigational Drugs 2009, 10:624-637 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The role of IL-2 and soluble IL-2R in depression and antidepressant response
T Eller, V Vasar, J Shlik, E Maron
Current Opinion in Investigational Drugs 2009, 10:638-643 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Injury and repair mechanisms in ischemic stroke: Considerations for the development of novel neurotherapeutics
E Candelario-Jalil
Current Opinion in Investigational Drugs 2009, 10:644-654 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
TRP channel antagonists for pain - opportunities beyond TRPV1
S Bevan, DA Andersson
Current Opinion in Investigational Drugs 2009, 10:655-663 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression
JW Koo, RS Duman
Current Opinion in Investigational Drugs 2009, 10:664-671 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The role of RAGE in amyloid-  peptide-mediated pathology in Alzheimer's disease
AM Schmidt, B Sahagan, RB Nelson, J Selmer, R Rothlein, JM Bell
Current Opinion in Investigational Drugs 2009, 10:672-680 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Central regulation of ejaculation and the therapeutic role of serotonergic agents in premature ejaculation
K Patel, WJG Hellstrom
Current Opinion in Investigational Drugs 2009, 10:681-690 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders
R Hardeland
Current Opinion in Investigational Drugs 2009, 10:691-701 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
NGX-4010, a high-concentration capsaicin dermal patch for lasting relief of peripheral neuropathic pain
C Noto, M Pappagallo, A Szallasi
Current Opinion in Investigational Drugs 2009, 10:702-710 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Telcagepant, a calcitonin gene-related peptide antagonist for the treatment of migraine
SJ Tepper, C Cleves
Current Opinion in Investigational Drugs 2009, 10:711-720 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Semagacestat, a gamma-secretase inhibitor for the potential treatment of Alzheimer's disease
BP Imbimbo, I Peretto
Current Opinion in Investigational Drugs 2009, 10:721-730 (30June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2009, 10:731-736 (30July2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:737-745 (30July2009)
[Abstract] [Full text] [PDF]
Influenza - The case for combination therapy
MR Krystal, NA Meanwell
Current Opinion in Investigational Drugs 2009, 10:746-749 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The use of ribosomal crystal structures in antibiotic drug design
BT Wimberly
Current Opinion in Investigational Drugs 2009, 10:750-765 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Bacteriophage therapy for the treatment of infections
A Grski, R Mi  dzybrodzki, J Borysowski, B Weber-D browska, M  obocka, W Fortuna, S Letkiewicz, M Zimecki, G Filby
Current Opinion in Investigational Drugs 2009, 10:766-774 (30July2009)
[Abstract] [Full text] [PDF]
Pharmacokinetic enhancers for HIV drugs
L Xu, MC Desai
Current Opinion in Investigational Drugs 2009, 10:775-786 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
The relevance of the polymicrobial nature of airway infection in the acute and chronic management of patients with cystic fibrosis
CD Sibley, MD Parkins, HR Rabin, MG Surette
Current Opinion in Investigational Drugs 2009, 10:787-794 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Hepatitis B: The case for combination therapy
S Bowden, T Shaw
Current Opinion in Investigational Drugs 2009, 10:795-803 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
New inhibitors of bacterial topoisomerase GyrA/ParC subunits
MT Black, K Coleman
Current Opinion in Investigational Drugs 2009, 10:804-810 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Measles control - Can measles virus inhibitors make a difference?
RK Plemper, JP Snyder
Current Opinion in Investigational Drugs 2009, 10:811-820 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
A review of HCV protease inhibitors
KX Chen, FG Njoroge
Current Opinion in Investigational Drugs 2009, 10:821-837 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
IPSAT P1A, a class A -lactamase therapy for the prevention of penicillin-induced disruption to the intestinal microflora
JDD Pitout
Current Opinion in Investigational Drugs 2009, 10:838-844 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Vicriviroc, a CCR5 receptor antagonist for the potential treatment
of HIV infection
OM Klibanov
Current Opinion in Investigational Drugs 2009, 10:845-859 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Celgosivir, an -glucosidase I inhibitor for the potential treatment of HCV infection
D Durantel
Current Opinion in Investigational Drugs 2009, 10:860-870 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
TMC-435, an NS3/4A protease inhibitor for the treatment of
HCV infection
YS Tsantrizos
Current Opinion in Investigational Drugs 2009, 10:871-881 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Retraction: Transplantation: Tolerance (COID (2003) 4(5):530-535)
Current Opinion in Investigational Drugs 2009, 10:882 (30July2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, N Levens, M Williams
Current Opinion in Investigational Drugs 2009, 10:883-889 (24August2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:890-898 (24August2009)
[Abstract] [Full text] [PDF]
Treatment of peripheral artery disease: An unmet medical need
WR Tracey, DR Knight
Current Opinion in Investigational Drugs 2009, 10:899-901 (24August2009)
[Abstract] [Full text] [PDF]
Novel antiplatelet therapies following percutaneous coronary interventions
I Ahrens, C Bode
Current Opinion in Investigational Drugs 2009, 10:902-911 (24August2009)
[Abstract] [Full text] [PDF]
The resurgence of thyromimetics as lipid-modifying agents
I Tancevski, P Eller, A Patsch JR Ritsch
Current Opinion in Investigational Drugs 2009, 10:912-918 (24August2009)
[Abstract] [Full text] [PDF]
Are vitamin D receptor activators useful for the treatment of thrombosis?
JR Wu-Wong
Current Opinion in Investigational Drugs 2009, 10:919-927 (24August2009)
[Abstract] [Full text] [PDF]
Signaling networks regulating cardiac myocyte survival and death
M Wagner, MAQ Siddiqui
Current Opinion in Investigational Drugs 2009, 10:928-937 (24August2009)
[Abstract] [Full text] [PDF]
Targeting PCSK9 for the treatment of hypercholesterolemia
JA Hedrick
Current Opinion in Investigational Drugs 2009, 10:938-946 (24August2009)
[Abstract] [Full text] [PDF]
The usefulness of coronary artery calcium scoring and computed tomography angiography to detect patients at high-risk for coronary heart disease
A Lembcke
Current Opinion in Investigational Drugs 2009, 10:947-954 (24August2009)
[Abstract] [Full text] [PDF]
The use of  3-adrenergic receptor agonists in the treatment of heart
failure
HH Rasmussen, GA Figtree, H Krum, H Bundgaard
Current Opinion in Investigational Drugs 2009, 10:955-962 (24August2009)
[Abstract] [Full text] [PDF]
The potential of TRPV1 agonists for treating ischemia/reperfusion-induced renal injuries
S Rayamajhi, T Contractor, DH Wang
Current Opinion in Investigational Drugs 2009, 10:963-970 (24August2009)
[Abstract] [Full text] [PDF]
Riociguat, an oral soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension
J Belik
Current Opinion in Investigational Drugs 2009, 10:971-979 (24August2009)
[Abstract] [Full text] [PDF]
Anacetrapib, a cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis
D Masson
Current Opinion in Investigational Drugs 2009, 10:980-987 (24August2009)
[Abstract] [Full text] [PDF]
SCH-530348, a thrombin receptor (PAR-1) antagonist for the prevention and treatment of atherothrombosis
J Oestreich
Current Opinion in Investigational Drugs 2009, 10:988-996 (24August2009)
[Abstract] [Full text] [PDF]
FX-06, a fibrin-derived B15-42 peptide for the potential treatment of reperfusion injury following myocardial infarction
I Ahrens, K Peter
Current Opinion in Investigational Drugs 2009, 10:997-1003 (24August2009)
[Abstract] [Full text] [PDF]
Erratum [West K: CP-690550, a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders. COID (2009) 10(5):491-504]
Current Opinion in Investigational Drugs 2009, 10:1004-1006 (24August2009)
[Abstract] [Full text] [PDF]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst, M Williams
Current Opinion in Investigational Drugs 2009, 10:1007-1012 (21September2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:1013-1021 (21September2009)
[Abstract] [Full text] [PDF]
Mitochondria - A neglected drug target
MP Murphy
Current Opinion in Investigational Drugs 2009, 10:1022-1024 (21September2009)
[Abstract] [Full text] [PDF]
The significance of new somatostatin analogs as therapeutic agents
MC Zatelli, ED Uberti
Current Opinion in Investigational Drugs 2009, 10:1025-1031 (21September2009)
[Abstract] [Full text] [PDF]
Resistance pathways relevant to insulin-like growth factor-1
receptor-targeted therapy
AW Hendrickson, P Haluska
Current Opinion in Investigational Drugs 2009, 10:1032-1040 (21September2009)
[Abstract] [Full text] [PDF]
Experimental antipsychotics and metabolic adverse effects - Findings
from clinical trials
A Tschoner, WW Fleischhacker, CF Ebenbichler
Current Opinion in Investigational Drugs 2009, 10:1041-1048 (21September2009)
[Abstract] [Full text] [PDF]
Insulin resistance and neurodegeneration: Roles of obesity, type 2
diabetes mellitus and non-alcoholic steatohepatitis
SM de la Monte, L Longato, M Tong, JR Wands
Current Opinion in Investigational Drugs 2009, 10:1049-1060 (21September2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Adipokines: Emerging therapeutic targets
K Kos, JPH Wilding
Current Opinion in Investigational Drugs 2009, 10:1061-1068 (21September2009)
[Abstract] [Full text] [PDF]
Antagonists of the renin-angiotensin system and the prevention of obesity
RS Weisinger, DP Begg, M Jois
Current Opinion in Investigational Drugs 2009, 10:1069-1077 (21September2009)
[Abstract] [Full text] [PDF]
Bariatric surgery: What is the effect on type 2 diabetes?
M Dar, WJ Pories
Current Opinion in Investigational Drugs 2009, 10:1078-1084 (21September2009)
[Abstract] [Full text] [PDF]
Bone as a target of type 2 diabetes treatment
B Lecka-Czernik
Current Opinion in Investigational Drugs 2009, 10:1085-1090 (21September2009)
[Abstract] [Full text] [PDF]
Linagliptin, a dipeptidyl peptidase-4 inhibitor for the treatment of
type 2 diabetes
A Tiwari
Current Opinion in Investigational Drugs 2009, 10:1091-1104 (21September2009)
[Abstract] [Full text] [PDF]
Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity
NT Bello, MR Zahner
Current Opinion in Investigational Drugs 2009, 10:1105-1116 (21September2009)
[Abstract] [Full text] [PDF]
Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity
R Padwal
Current Opinion in Investigational Drugs 2009, 10:1117-1125 (21September2009)
[Abstract] [Full text] [PDF]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst
Current Opinion in Investigational Drugs 2009, 10:1127-1132 (27October2009)
[Abstract] [Full text] [PDF]
Patent alert
HAm Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:1133-1140 (27October2009)
[Abstract] [Full text] [PDF]
Editorial Overview - Something old, something new - Colchicine in the 21st century
BN Cronstein
Current Opinion in Investigational Drugs 2009, 10:1141-1142 (27October2009)
[Abstract] [Full text] [PDF]
Gene therapy approaches to induce tolerance in autoimmunity by reshaping the immune system
CH Wasserfall, RW Herzog
Current Opinion in Investigational Drugs 2009, 10:1143-1150 (27October2009)
[Abstract] [Full text] [PDF]
PI3K isoforms as drug targets in inflammatory diseases: Lessons from pharmacological and genetic strategies
SJ Harris, JG Foster, SG Ward
Current Opinion in Investigational Drugs 2009, 10:1151-1162 (27October2009)
[Abstract] [Full text] [PDF]
FLAP inhibitors for the treatment of inflammatory diseases
AP Sampson
Current Opinion in Investigational Drugs 2009, 10:1163-1172 (27October2009)
[Abstract] [Full text] [PDF]
Modulation of inflammatory disease by inhibitors of leukotriene A4 hydrolase
AM Fourie
Current Opinion in Investigational Drugs 2009, 10:1173-1182 (27October2009)
[Abstract] [Full text] [PDF]
The role of sphingosine-1-phosphate receptor modulators in the prevention of transplant rejection and autoimmune diseases
L Japtok, B Kleuser
Current Opinion in Investigational Drugs 2009, 10:1183-1194 (27October2009)
[Abstract] [Full text] [PDF]
Regulation of osteoclast precursors in inflammatory bone loss
L Xing
Current Opinion in Investigational Drugs 2009, 10:1195-1203 (27October2009)
[Abstract] [Full text] [PDF]
Anti-cytokine antibodies for rheumatic diseases
F Atzeni, P Sarzi-Puttini
Current Opinion in Investigational Drugs 2009, 10:1204-1211 (27October2009)
[Abstract] [Full text] [PDF]
The development of nanobodies for therapeutic applications
F Van Bockstaele, J-B Holz, H Revets
Current Opinion in Investigational Drugs 2009, 10:1212-1224 (27October2009)
[Abstract] [Full text] [PDF]
Sotrastaurin, a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis
S Manicassamy
Current Opinion in Investigational Drugs 2009, 10:1225-1235 (27October2009)
[Abstract] [Full text] [PDF]
AN-2728, a PDE4 inhibitor for the potential topical treatment of psoriasis and atopic dermatitis
R Nazarian, JM Weinberg
Current Opinion in Investigational Drugs 2009, 10:1236-1242 (27October2009)
[Abstract] [Full text] [PDF]
Palovarotene, a novel retinoic acid receptor  agonist for the treatment of emphysema
M Hind, S Stinchcombe
Current Opinion in Investigational Drugs 2009, 10:1243-1250 (27October2009)
[Abstract] [Full text] [PDF]
Paper alert
SA Antoniu, M Daneshtalab, S Doggrell, MJ Elices, RE Hurst
Current Opinion in Investigational Drugs 2009, 10:1251-1256 (20November2009)
[Abstract] [Full text] [PDF]
Patent alert
HAM Mucke, P Norman, C Yeates
Current Opinion in Investigational Drugs 2009, 10:1257-1265 (20November2009)
[Abstract] [Full text] [PDF]
Kinase inhibitor selectivity
SS Bhagwat
Current Opinion in Investigational Drugs 2009, 10:1266-1268 (20November2009)
[Abstract] [Full text] [PDF]
Autophagy inhibition in combination cancer treatment
KM Livesey, D Tang, HJ Zeh, MT Lotze
Current Opinion in Investigational Drugs 2009, 10:1269-1279 (20November2009)
[Abstract] [Full text] [PDF]
Microbial antitumor drugs: Natural products of microbial origin as anticancer agents
DJ Newman, GM Cragg
Current Opinion in Investigational Drugs 2009, 10:1280-1296 (20November2009)
[Abstract] [Full text] [PDF]
Phosphatases as targets for cancer treatment
JS Lazo, P Wipf
Current Opinion in Investigational Drugs 2009, 10:1297-1304 (20November2009)
[Abstract] [Full text] [PDF]
The role of KRAS mutations in resistance to EGFR inhibition in the treatment of cancer
A Lopez-Chavez, CA Carter, G Giaccone
Current Opinion in Investigational Drugs 2009, 10:1305-1314 (20November2009)
[Abstract] [Full text] [PDF]
GM-CSF-secreting vaccines for solid tumors
LA Emens
Current Opinion in Investigational Drugs 2009, 10:1315-1324 (20November2009)
[Abstract] [Full text] [PDF]
Combination chemotherapy for head and neck cancer: The addition of Bcl-2 inhibitors
L Lo Russo, L Lo Muzio
Current Opinion in Investigational Drugs 2009, 10:1325-1333 (20November2009)
[Abstract] [Full text] [PDF]
Antiangiogenic therapies in breast cancer
R Sarmiento, MR D'Andrea, F Cacciamani, F Salerno, G Gasparini
Current Opinion in Investigational Drugs 2009, 10:1334-1345 (20November2009)
[Abstract] [Full text] [PDF]
Alpharadin, a 223Ra-based  -particle-emitting pharmaceutical for the treatment of bone metastases in patients with cancer
K Liepe
Current Opinion in Investigational Drugs 2009, 10:1346-1358 (20November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
Sagopilone, a microtubule stabilizer for the potential treatment of cancer
CM Galmarini
Current Opinion in Investigational Drugs 2009, 10:1359-1371 (20November2009)
[Abstract] [Full text] [PDF]
JX-594, a targeted oncolytic poxvirus for the treatment of cancer
AE Merrick, EJ Ilett, AA Melcher
Current Opinion in Investigational Drugs 2009, 10:1372-1382 (20November2009)
[Abstract] [Full text] [PDF]
TRU-016, a humanized anti-CD37 IgG fusion protein for the potential treatment of B-cell malignancies
T Robak, P Robak, P Smolewski
Current Opinion in Investigational Drugs 2009, 10:1383-1390 (20November2009)
[Abstract] [Full text] [PDF]
Contents Index - Volume 10
Current Opinion in Investigational Drugs 2009, 10:1391-1398 (20November2009)
[Abstract] [Full text] [PDF]
Author Index - Volume 10
Current Opinion in Investigational Drugs 2009, 10:1399-1401 (20November2009)
[Abstract] [Full text] [PDF]
Subject Index - Volume 10
Current Opinion in Investigational Drugs 2009, 10:1402-1406 (20November2009)
[Abstract] [Full text] [PDF]
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