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Open Access Highly Accessed Commentary

Commentary: the role of cytologic analysis of voided urine in the work-up of asymptomatic microhematuria

Deep Trivedi and Edward M Messing*

Author Affiliations

Department of Urology, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA

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BMC Urology 2009, 9:13  doi:10.1186/1471-2490-9-13

Published: 10 September 2009

Abstract

Microscopic hematuria is a common finding in patients presenting to both primary care doctors as well as urologists. Sources of microscopic hematuria include infection, stones, inflammatory disorders as well as cancer of the genitourinary tract, particularly urothelial cancer. A primary focus in the urologic workup of hematuria is to rule out cancer. This is done using radiographic studies as well as procedures such as cystoscopy and bladder biopsy. As the authors state in their article titled "The utility of serial urinary cytology in the initial evaluation of the patient with microscopic hematuria", cytologic analysis of voided urine, though attractive due to its noninvasive nature, has been found to have the neither the sensitivity, cost-effectiveness, nor the ease of administration necessary to replace more invasive diagnostics in the evaluation of microscopic hematuria.