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Open Access Highly Accessed Commentary

Prostate Cancer – To screen, or not to screen, is that the question?

Charles J Rosser

Author Affiliations

Department of Urology and Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, USA

BMC Urology 2008, 8:20  doi:10.1186/1471-2490-8-20

Published: 23 December 2008

Abstract

There continues to be controversy regarding serum Prostate-Specific Antigen (PSA) and prostate cancer screening. We anxiously await the results of two large prospective randomized clinical trials (Prostate, Lung, Colon, and Ovary-PCLO screening trial in the US and European Randomized Study of Screening for Prostate Cancer-ERSPC in Europe) assessing the benefits of prostate cancer screening. However the true question to answer may be which cancer to treat and when should we treat it.