Table 5

Cox proportional hazards univariate and multivariate analysis of progression after primary transurethral resection for T1 bladder carcinoma in the Southeast care region in Sweden 19922001
Univariate Hazard ratio (95% CI) Multivariate Hazard ratio (95% CI) p-value
LVI*
 No 1.0 1.0
 Suspected 1.01 (0.51–2.00) 0.84 (0.42–1.68) 0.70
 Yes 3.10 (1.48–6.49) 3.84 (1.75–8.42) 0.001
p16
 Abnormal 1.0 1.0
 Normal 0.40 (0.23–0.74) 0.37 (0.19–0.69) 0.002
p21
 Abnormal 1.0 1.0
 Normal 1.93 (0.77–4.86) 1.39 (0.54–3.59) 0.50
p53
 Abnormal 1.0 1.0
 Normal 0.75 (0.42–1.35) 1.54 (0.84–2.82) 0.17
p53 mutation
 No 1.0 1.0
 Yes 1.51 (0.87–2.59) 1.28 (0.73–2.23) 0.38
MDM2 T/T
 No 1.0 1.0
 Yes 1.52 (0.89–2.62) 1.75 (1.00–3.06) 0.052
pRb
 Abnormal 1.0 1.0
 Normal 1.36 (0.70–2.65) 1.58 (0.79–3.17) 0.20

*LVI = lymphovascular invasion.

Olsson et al.

Olsson et al. BMC Urology 2013 13:5   doi:10.1186/1471-2490-13-5

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