Figure 2.

G2/M Arrest after Ionizing Radiation DNA Damage. Activation of ATM and ATR by DNA damage produces G2 arrest. Once DNA is repaired Cdc25c is inactivated which stimulates Cdc2 and enhances cell entry into mitosis by Cyclin B.

Palacios et al. BMC Urology 2013 13:4   doi:10.1186/1471-2490-13-4
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